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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1973 1
1977 1
1986 1
1987 1
1988 1
1989 3
1990 2
1991 1
1992 5
1993 2
1994 2
1995 4
1996 3
1997 2
1998 1
1999 3
2000 4
2001 9
2002 6
2003 6
2004 12
2005 10
2006 12
2007 14
2008 14
2009 17
2010 17
2011 27
2012 35
2013 43
2014 63
2015 57
2016 67
2017 86
2018 112
2019 113
2020 163
2021 191
2022 192
2023 199
2024 74

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1,405 results

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Page 1
Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer.
Jia D, Wang Q, Qi Y, Jiang Y, He J, Lin Y, Sun Y, Xu J, Chen W, Fan L, Yan R, Zhang W, Ren G, Xu C, Ge Q, Wang L, Liu W, Xu F, Wu P, Wang Y, Chen S, Wang L. Jia D, et al. Cell. 2024 Mar 28;187(7):1651-1665.e21. doi: 10.1016/j.cell.2024.02.022. Epub 2024 Mar 14. Cell. 2024. PMID: 38490195
IPA modulates the stemness program of CD8(+) T cells and facilitates the generation of progenitor exhausted CD8(+) T cells (T(pex)) by increasing H3K27 acetylation at the super-enhancer region of Tcf7. IPA improves ICB responsiveness at the pan-cancer level, including mela …
IPA modulates the stemness program of CD8(+) T cells and facilitates the generation of progenitor exhausted CD8(+) T cells (T(pex)) by incre …
Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1.
Chen S, Cui W, Chi Z, Xiao Q, Hu T, Ye Q, Zhu K, Yu W, Wang Z, Yu C, Pan X, Dai S, Yang Q, Jin J, Zhang J, Li M, Yang D, Yu Q, Wang Q, Yu X, Yang W, Zhang X, Qian J, Ding K, Wang D. Chen S, et al. Cell Metab. 2022 Nov 1;34(11):1843-1859.e11. doi: 10.1016/j.cmet.2022.08.016. Epub 2022 Sep 13. Cell Metab. 2022. PMID: 36103895 Free article.
In particular, intratumoral high potassium (K(+)) has shown immune-suppressive potency on T cells. However, as a pan-cancer characteristic associated with local necrosis, the impact of this ionic disturbance on innate immunity is unknown. ...
In particular, intratumoral high potassium (K(+)) has shown immune-suppressive potency on T cells. However, as a pan-cancer character …
Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis.
Yu M, Yi J, Qiu Q, Yao D, Li J, Yang J, Mi C, Zhou L, Lu B, Lu W, Ying K, Chen W, Chen E, Zhang H, Lu Z, Lu Y, Liu P. Yu M, et al. Cell Rep. 2023 Nov 28;42(11):113408. doi: 10.1016/j.celrep.2023.113408. Epub 2023 Nov 9. Cell Rep. 2023. PMID: 37943661 Free article.
However, the role of tRFs in cancer progression remains largely elusive. Here, we demonstrate that a pan-cancer 3'-tRF, CAT1 (cancer associated tRF 1), is ubiquitously upregulated in tumors and associated with poor prognosis of a variety of cancers, including lung cancer. …
However, the role of tRFs in cancer progression remains largely elusive. Here, we demonstrate that a pan-cancer 3'-tRF, CAT1 (cancer …
Identification and validation of SERPINE1 as a prognostic and immunological biomarker in pan-cancer and in ccRCC.
Li L, Li F, Xu Z, Li L, Hu H, Li Y, Yu S, Wang M, Gao L. Li L, et al. Front Pharmacol. 2023 Aug 23;14:1213891. doi: 10.3389/fphar.2023.1213891. eCollection 2023. Front Pharmacol. 2023. PMID: 37680718 Free PMC article.
However, its clinical significance and potential mechanisms in pan-cancer remain obscure. Methods: In pan-cancer multi-omics data from public datasets, including The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx), and online web tools were used to …
However, its clinical significance and potential mechanisms in pan-cancer remain obscure. Methods: In pan-cancer multi-omics d …
Large-scale comparative analysis of microbial pan-genomes using PanOCT.
Inman JM, Sutton GG, Beck E, Brinkac LM, Clarke TH, Fouts DE. Inman JM, et al. Bioinformatics. 2019 Mar 15;35(6):1049-1050. doi: 10.1093/bioinformatics/bty744. Bioinformatics. 2019. PMID: 30165579 Free PMC article.
SUMMARY: The JCVI pan-genome pipeline is a collection of programs to run PanOCT and tools that support and extend the capabilities of PanOCT. ...The JCVI Pan-Genome Pipeline wrapper invokes command-line utilities that prepare input genomes, invoke third-party …
SUMMARY: The JCVI pan-genome pipeline is a collection of programs to run PanOCT and tools that support and extend the capabili …
Structural genomics of the human dopamine receptor system.
Xu P, Huang S, Krumm BE, Zhuang Y, Mao C, Zhang Y, Wang Y, Huang XP, Liu YF, He X, Li H, Yin W, Jiang Y, Zhang Y, Roth BL, Xu HE. Xu P, et al. Cell Res. 2023 Aug;33(8):604-616. doi: 10.1038/s41422-023-00808-0. Epub 2023 May 23. Cell Res. 2023. PMID: 37221270
Here, we report cryo-EM structures of all five subtypes of human dopamine receptors in complex with G protein and bound to the pan-agonist, rotigotine, which is used to treat PD and restless legs syndrome. ...
Here, we report cryo-EM structures of all five subtypes of human dopamine receptors in complex with G protein and bound to the pan-ag …
The Expression Characteristics and Function of the RECQ Family in Pan-Cancer.
Zhou Y, Huang X, Wang L, Luo Y. Zhou Y, et al. Biomedicines. 2023 Aug 21;11(8):2318. doi: 10.3390/biomedicines11082318. Biomedicines. 2023. PMID: 37626815 Free PMC article.
BACKGROUND: The genes of the RECQ DNA helicase family play a part in preserving the stability of the genome and controlling different disease mechanisms. However, the expression features of RECQs in relation to pan-cancer, their correlation with the immune microenvironment …
BACKGROUND: The genes of the RECQ DNA helicase family play a part in preserving the stability of the genome and controlling different diseas …
1,405 results