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Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder.
Yang W, Zerbe H, Petzl W, Brunner RM, Günther J, Draing C, von Aulock S, Schuberth HJ, Seyfert HM. Yang W, et al. Among authors: brunner rm. Mol Immunol. 2008 Mar;45(5):1385-97. doi: 10.1016/j.molimm.2007.09.004. Epub 2007 Oct 22. Mol Immunol. 2008. PMID: 17936907