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2014 2
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2018 5
2019 1
2021 1
2023 1
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18 results

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SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Lospinoso Severini L, Loricchio E, Navacci S, Basili I, Alfonsi R, Bernardi F, Moretti M, Conenna M, Cucinotta A, Coni S, Petroni M, De Smaele E, Giannini G, Maroder M, Canettieri G, Mastronuzzi A, Guardavaccaro D, Ayrault O, Infante P, Bufalieri F, Di Marcotullio L. Lospinoso Severini L, et al. Among authors: alfonsi r. Cell Death Differ. 2024 Feb;31(2):170-187. doi: 10.1038/s41418-023-01246-6. Epub 2023 Dec 7. Cell Death Differ. 2024. PMID: 38062245 Free PMC article.
Targeting GLI factors to inhibit the Hedgehog pathway.
Infante P, Alfonsi R, Botta B, Mori M, Di Marcotullio L. Infante P, et al. Among authors: alfonsi r. Trends Pharmacol Sci. 2015 Aug;36(8):547-58. doi: 10.1016/j.tips.2015.05.006. Epub 2015 Jun 10. Trends Pharmacol Sci. 2015. PMID: 26072120 Review.
Insights into Gli Factors Ubiquitylation Methods.
Infante P, Alfonsi R, Di Marcotullio L. Infante P, et al. Among authors: alfonsi r. Methods Mol Biol. 2015;1322:131-46. doi: 10.1007/978-1-4939-2772-2_12. Methods Mol Biol. 2015. PMID: 26179045
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazzà D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: alfonsi r. Nat Commun. 2018 Mar 7;9(1):976. doi: 10.1038/s41467-018-03339-0. Nat Commun. 2018. PMID: 29515120 Free PMC article.
Renal cancer: new models and approach for personalizing therapy.
di Martino S, De Luca G, Grassi L, Federici G, Alfonsi R, Signore M, Addario A, De Salvo L, Francescangeli F, Sanchez M, Tirelli V, Muto G, Sperduti I, Sentinelli S, Costantini M, Pasquini L, Milella M, Haoui M, Simone G, Gallucci M, De Maria R, Bonci D. di Martino S, et al. Among authors: alfonsi r. J Exp Clin Cancer Res. 2018 Sep 5;37(1):217. doi: 10.1186/s13046-018-0874-4. J Exp Clin Cancer Res. 2018. PMID: 30185225 Free PMC article.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: alfonsi r. EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4. EMBO J. 2015. PMID: 25476449 Free PMC article.
Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancer.
Signore M, Alfonsi R, Federici G, Nanni S, Addario A, Bertuccini L, Aiello A, Di Pace AL, Sperduti I, Muto G, Giacobbe A, Collura D, Brunetto L, Simone G, Costantini M, Crinò L, Rossi S, Tabolacci C, Diociaiuti M, Merlino T, Gallucci M, Sentinelli S, Papalia R, De Maria R, Bonci D. Signore M, et al. Among authors: alfonsi r. Cell Death Dis. 2021 Jun 21;12(7):636. doi: 10.1038/s41419-021-03909-z. Cell Death Dis. 2021. PMID: 34155195 Free PMC article.
Click Reaction as a Tool to Combine Pharmacophores: The Case of Vismodegib.
Christodoulou MS, Mori M, Pantano R, Alfonsi R, Infante P, Botta M, Damia G, Ricci F, Sotiropoulou PA, Liekens S, Botta B, Passarella D. Christodoulou MS, et al. Among authors: alfonsi r. Chempluschem. 2015 Jun;80(6):938-943. doi: 10.1002/cplu.201402435. Epub 2015 Feb 27. Chempluschem. 2015. PMID: 31973263
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Grassi L, Alfonsi R, Francescangeli F, Signore M, De Angelis ML, Addario A, Costantini M, Flex E, Ciolfi A, Pizzi S, Bruselles A, Pallocca M, Simone G, Haoui M, Falchi M, Milella M, Sentinelli S, Di Matteo P, Stellacci E, Gallucci M, Muto G, Tartaglia M, De Maria R, Bonci D. Grassi L, et al. Among authors: alfonsi r. Cell Death Dis. 2019 Feb 27;10(3):201. doi: 10.1038/s41419-019-1453-0. Cell Death Dis. 2019. PMID: 30814510 Free PMC article.
18 results