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Page 1
Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma.
Zhang X, Zegar T, Weiser T, Hamdan FH, Berger BT, Lucas R, Balourdas DI, Ladigan S, Cheung PF, Liffers ST, Trajkovic-Arsic M, Scheffler B, Joerger AC, Hahn SA, Johnsen SA, Knapp S, Siveke JT. Zhang X, et al. Among authors: lucas r. Int J Cancer. 2020 Nov 15;147(10):2847-2861. doi: 10.1002/ijc.33137. Epub 2020 Jun 29. Int J Cancer. 2020. PMID: 32599645 Free article.
Synthesis and Antiproliferative Effect of Ethyl 4-[4-(4-Substituted Piperidin-1-yl)]benzylpyrrolo[1,2-a]quinoxalinecarboxylate Derivatives on Human Leukemia Cells.
Desplat V, Vincenzi M, Lucas R, Moreau S, Savrimoutou S, Rubio S, Pinaud N, Bigat D, Enriquez E, Marchivie M, Routier S, Sonnet P, Rossi F, Ronga L, Guillon J. Desplat V, et al. Among authors: lucas r. ChemMedChem. 2017 Jun 21;12(12):940-953. doi: 10.1002/cmdc.201700049. Epub 2017 Apr 5. ChemMedChem. 2017. PMID: 28218826
Synthesis and evaluation of the antiproliferative activity of novel isoindolo[2,1-a]quinoxaline and indolo[1,2-a]quinoxaline derivatives.
Desplat V, Moreau S, Belisle-Fabre S, Thiolat D, Uranga J, Lucas R, de Moor L, Massip S, Jarry C, Mossalayi DM, Sonnet P, Déléris G, Guillon J. Desplat V, et al. Among authors: lucas r. J Enzyme Inhib Med Chem. 2011 Oct;26(5):657-67. doi: 10.3109/14756366.2010.548326. Epub 2011 Jan 21. J Enzyme Inhib Med Chem. 2011. PMID: 21250818
Synthesis and evaluation of the cytotoxic activity of novel ethyl 4-[4-(4-substitutedpiperidin-1-yl)]benzyl-phenylpyrrolo[1,2-a]quinoxaline-carboxylate derivatives in myeloid and lymphoid leukemia cell lines.
Desplat V, Vincenzi M, Lucas R, Moreau S, Savrimoutou S, Pinaud N, Lesbordes J, Peyrilles E, Marchivie M, Routier S, Sonnet P, Rossi F, Ronga L, Guillon J. Desplat V, et al. Among authors: lucas r. Eur J Med Chem. 2016 May 4;113:214-27. doi: 10.1016/j.ejmech.2016.02.047. Epub 2016 Feb 20. Eur J Med Chem. 2016. PMID: 26945110