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A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor response.
Oncoimmunology. 2023 Apr 24;12(1):2205336. doi: 10.1080/2162402X.2023.2205336. eCollection 2023.
Oncoimmunology. 2023.
PMID: 37114242
Free PMC article.
Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2.
Lázaro-Gorines R, Pérez P, Heras-Murillo I, Adán-Barrientos I, Albericio G, Astorgano D, Flores S, Luczkowiak J, Labiod N, Harwood SL, Segura-Tudela A, Rubio-Pérez L, Nugraha Y, Shang X, Li Y, Alfonso C, Adipietro KA, Abeyawardhane DL, Navarro R, Compte M, Yu W, MacKerell AD Jr, Sanz L, Weber DJ, Blanco FJ, Esteban M, Pozharski E, Godoy-Ruiz R, Muñoz IG, Delgado R, Sancho D, García-Arriaza J, Álvarez-Vallina L.
Lázaro-Gorines R, et al.
Adv Sci (Weinh). 2023 Dec;10(34):e2304818. doi: 10.1002/advs.202304818. Epub 2023 Oct 20.
Adv Sci (Weinh). 2023.
PMID: 37863812
Free PMC article.
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Fungal Ribotoxins: A Review of Potential Biotechnological Applications.
Olombrada M, Lázaro-Gorines R, López-Rodríguez JC, Martínez-Del-Pozo Á, Oñaderra M, Maestro-López M, Lacadena J, Gavilanes JG, García-Ortega L.
Olombrada M, et al. Among authors: lazaro gorines r.
Toxins (Basel). 2017 Feb 21;9(2):71. doi: 10.3390/toxins9020071.
Toxins (Basel). 2017.
PMID: 28230789
Free PMC article.
Review.
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Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicity.
Hangiu O, Compte M, Dinesen A, Navarro R, Tapia-Galisteo A, Mandrup OA, Erce-Llamazares A, Lázaro-Gorines R, Nehme-Álvarez D, Domínguez-Alonso C, Harwood SL, Alfonso C, Blanco B, Rubio-Pérez L, Jiménez-Reinoso A, Díez-Alonso L, Blanco FJ, Sanz L, Howard KA, Álvarez-Vallina L.
Hangiu O, et al. Among authors: lazaro gorines r.
iScience. 2022 Aug 17;25(9):104958. doi: 10.1016/j.isci.2022.104958. eCollection 2022 Sep 16.
iScience. 2022.
PMID: 36072551
Free PMC article.
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Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy.
Lázaro-Gorines R, López-Rodríguez JC, Benedé S, González M, Mayorga C, Vogel L, Martínez-Del-Pozo Á, Lacadena J, Villalba M.
Lázaro-Gorines R, et al.
Sci Rep. 2020 Jul 23;10(1):12255. doi: 10.1038/s41598-020-69166-w.
Sci Rep. 2020.
PMID: 32703972
Free PMC article.
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Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins.
Ruiz-de-la-Herrán J, Tomé-Amat J, Lázaro-Gorines R, Gavilanes JG, Lacadena J.
Ruiz-de-la-Herrán J, et al. Among authors: lazaro gorines r.
Toxins (Basel). 2019 Oct 12;11(10):593. doi: 10.3390/toxins11100593.
Toxins (Basel). 2019.
PMID: 31614771
Free PMC article.
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