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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O'Neill LAJ. Runtsch MC, et al. Among authors: chirillo r. Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002. Cell Metab. 2022. PMID: 35235776 Free article.
Chemoresistance in H-Ferritin Silenced Cells: The Role of NF-κB.
Aversa I, Chirillo R, Chiarella E, Zolea F, Di Sanzo M, Biamonte F, Palmieri C, Costanzo F. Aversa I, et al. Among authors: chirillo r. Int J Mol Sci. 2018 Sep 28;19(10):2969. doi: 10.3390/ijms19102969. Int J Mol Sci. 2018. PMID: 30274235 Free PMC article.
H-Ferritin Affects Cisplatin-Induced Cytotoxicity in Ovarian Cancer Cells through the Modulation of ROS.
Salatino A, Aversa I, Battaglia AM, Sacco A, Di Vito A, Santamaria G, Chirillo R, Veltri P, Tradigo G, Di Cello A, Venturella R, Biamonte F, Costanzo F. Salatino A, et al. Among authors: chirillo r. Oxid Med Cell Longev. 2019 Oct 31;2019:3461251. doi: 10.1155/2019/3461251. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31781333 Free PMC article.
Genome-wide analysis of copy number alterations led to the characterisation of PDCD10 as oncogene in ovarian cancer.
De Marco C, Zoppoli P, Rinaldo N, Morganella S, Morello M, Zuccalà V, Carriero MV, Malanga D, Chirillo R, Bruni P, Malzoni C, Di Vizio D, Venturella R, Zullo F, Rizzuto A, Ceccarelli M, Ciliberto G, Viglietto G. De Marco C, et al. Among authors: chirillo r. Transl Oncol. 2021 Mar;14(3):101013. doi: 10.1016/j.tranon.2021.101013. Epub 2021 Jan 27. Transl Oncol. 2021. PMID: 33516089 Free PMC article.