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Page 1
Asthma and Respiratory Foundation NZ Adolescent and Adult Asthma Guidelines 2020: a quick reference guide.
Beasley R, Beckert L, Fingleton J, Hancox RJ, Harwood M, Hurst M, Jones S, Jones S, Kearns C, McNamara D, Poot B, Reid J. Beasley R, et al. N Z Med J. 2020 Jun 26;133(1517):73-99. N Z Med J. 2020. PMID: 32595223 Review.
The main changes in the 2020 update are: 1) combining the recommendations for both adolescents and adults in a single document, 2) the recommendation to avoid SABA-only treatment in the long-term management of asthma, 3) the use of budesonide/formoterol reliever, with or without …
The main changes in the 2020 update are: 1) combining the recommendations for both adolescents and adults in a single document, 2) the recom …
Asthma Medication Regimens in Pregnancy: Longitudinal Changes in Asthma Status.
Rohn MCH, Stevens DR, Kanner J, Nobles C, Chen Z, Grantz KL, Sherman S, Grobman WA, Kumar R, Biggio J, Mendola P. Rohn MCH, et al. Am J Perinatol. 2023 Jan;40(2):172-180. doi: 10.1055/s-0041-1727233. Epub 2021 Apr 21. Am J Perinatol. 2023. PMID: 33882589 Free PMC article.
CONCLUSION: Pregnant women taking SABA + ICS and SABA + ICS + LABA had better lung function in the first trimester. SABA + ICS + LABA was associated with improvements in lung function and inflammation across gestation. However, both the SABA + ICS and SABA + ICS + …
CONCLUSION: Pregnant women taking SABA + ICS and SABA + ICS + LABA had better lung function in the first trimester. SABA + ICS + L …
Management of asthma and chronic obstructive pulmonary disease with combination inhaled corticosteroids and long-acting β-agonists: a review of comparative effectiveness research.
Mapel DW, Roberts MH. Mapel DW, et al. Drugs. 2014 May;74(7):737-55. doi: 10.1007/s40265-014-0214-8. Drugs. 2014. PMID: 24797158 Free PMC article. Review.
The value of combination therapy with inhaled corticosteroids and long-acting beta-agonists (ICS/LABA) is well recognized in the management of asthma and chronic obstructive pulmonary disease (COPD). ...In contrast, a few recently reported real-world comparative effectiven …
The value of combination therapy with inhaled corticosteroids and long-acting beta-agonists (ICS/LABA) is well recognized in the mana …
Genome-wide association studies of exacerbations in children using long-acting beta2-agonists.
Slob EMA, Richards LB, Vijverberg SJH, Longo C, Koppelman GH, Pijnenburg MWH, Bel EHD, Neerincx AH, Herrera Luis E, Perez-Garcia J, Tim Chew F, Yie Sio Y, Andiappan AK, Turner SW, Mukhopadhyay S, Palmer CNA, Hawcutt D, Jorgensen AL, Burchard EG, Hernandez-Pacheco N, Pino-Yanes M, Maitland-van der Zee AH. Slob EMA, et al. Pediatr Allergy Immunol. 2021 Aug;32(6):1197-1207. doi: 10.1111/pai.13494. Epub 2021 Mar 29. Pediatr Allergy Immunol. 2021. PMID: 33706416 Free PMC article.
BACKGROUND: Some children with asthma experience exacerbations despite long-acting beta2-agonist (LABA) treatment. While this variability is partly caused by genetic variation, no genome-wide study until now has investigated which genetic factors associated with risk of ex …
BACKGROUND: Some children with asthma experience exacerbations despite long-acting beta2-agonist (LABA) treatment. While this variabi …
Initial maintenance therapy adherence among older adults with asthma-COPD overlap.
Nili M, LeMasters TJ, Adelman M, Dwibedi N, Madhavan SS, Sambamoorthi U. Nili M, et al. Am J Manag Care. 2021 Nov;27(11):463-470. doi: 10.37765/ajmc.2021.88773. Am J Manag Care. 2021. PMID: 34784138 Free article.
Those who were initiated on ICS/LABA were less likely to have persistent low adherence (unadjusted odds ratio [OR], 0.44; 95% CI, 0.29-0.67) compared with those initiated on ICS monotherapy when "persistent high adherence" was used as the reference group. The relationship …
Those who were initiated on ICS/LABA were less likely to have persistent low adherence (unadjusted odds ratio [OR], 0.44; 95% CI, 0.2 …
Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.
Wechsler ME, Szefler SJ, Ortega VE, Pongracic JA, Chinchilli V, Lima JJ, Krishnan JA, Kunselman SJ, Mauger D, Bleecker ER, Bacharier LB, Beigelman A, Benson M, Blake KV, Cabana MD, Cardet JC, Castro M, Chmiel JF, Covar R, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Grossman N, Holguin F, Jackson DJ, Kumar H, Kraft M, LaForce CF, Lang J, Lazarus SC, Lemanske RF Jr, Long D, Lugogo N, Martinez F, Meyers DA, Moore WC, Moy J, Naureckas E, Olin JT, Peters SP, Phipatanakul W, Que L, Raissy H, Robison RG, Ross K, Sheehan W, Smith LJ, Solway J, Sorkness CA, Sullivan-Vedder L, Wenzel S, White S, Israel E; NHLBI AsthmaNet. Wechsler ME, et al. N Engl J Med. 2019 Sep 26;381(13):1227-1239. doi: 10.1056/NEJMoa1905560. N Engl J Med. 2019. PMID: 31553835 Free PMC article. Clinical Trial.
Data indicate that patients with inadequately controlled asthma benefit more from addition of a long-acting beta-agonist (LABA) than from increased glucocorticoids; however, these data may not be informative for treatment in black patients. ...We compared combinations of t …
Data indicate that patients with inadequately controlled asthma benefit more from addition of a long-acting beta-agonist (LABA) than …
A randomized, crossover, placebo controlled, double-blind trial of the effects of tiotropium-olodaterol on neuromuscular performance during exercise in COPD.
Cao M, Calmelat RA, Kierstead P, Carraro N, Stringer WW, Porszasz J, Casaburi R, Rossiter HB. Cao M, et al. J Appl Physiol (1985). 2022 May 1;132(5):1145-1153. doi: 10.1152/japplphysiol.00332.2021. Epub 2022 Mar 24. J Appl Physiol (1985). 2022. PMID: 35323052 Free PMC article. Clinical Trial.
We, therefore, tested whether combination long-acting beta-agonist and muscarinic antagonist bronchodilator therapy [long-acting muscarinic antagonist (LAMA) + long-acting beta-agonist (LABA); Stiolto Respimat] would ameliorate the decline in neuromuscular performance and …
We, therefore, tested whether combination long-acting beta-agonist and muscarinic antagonist bronchodilator therapy [long-acting muscarinic …
Seasonal changes in prescribing of long-acting beta-2-agonists-containing drugs.
Rottenkolber M, Voogd E, van Dijk L, Primatesta P, Becker C, de Groot MC, Plana E, Alvarez Y, Durand J, Slattery J, Afonso A, Requena G, Huerta C, Alvarez A, de Abajo F, Tauscher M, Hasford J, Fischer R, Reynolds R, Schmiedl S. Rottenkolber M, et al. Respir Med. 2015 Jul;109(7):828-37. doi: 10.1016/j.rmed.2015.01.010. Epub 2015 Jan 31. Respir Med. 2015. PMID: 25976384 Free article.
Hence, we aimed to compare seasonal changes in prescription rates of long-acting beta-2-agonist (LABA) in four European countries. METHODS: A common study protocol was applied to six health care databases (Germany, Spain, the Netherlands (2), and the UK (2)) to calculate a …
Hence, we aimed to compare seasonal changes in prescription rates of long-acting beta-2-agonist (LABA) in four European countries. ME …
Trends in Omalizumab Utilization for Asthma: Evidence of Suboptimal Patient Selection.
Jeffery MM, Shah ND, Karaca-Mandic P, Ross JS, Rank MA. Jeffery MM, et al. J Allergy Clin Immunol Pract. 2018 Sep-Oct;6(5):1568-1577.e4. doi: 10.1016/j.jaip.2017.07.034. Epub 2017 Sep 22. J Allergy Clin Immunol Pract. 2018. PMID: 28958746
A comparison cohort (1:5 matching proportion) of nonomalizumab users was compared with incident omalizumab users on demographic characteristics, medication adherence (medication possession ratio [MPR]) for ICSs and/or ICS/long-acting beta-agonist (ICS-LABA), exacerbation f …
A comparison cohort (1:5 matching proportion) of nonomalizumab users was compared with incident omalizumab users on demographic characterist …
The IMPACT of triple versus dual single-inhaler therapy on exacerbations of COPD.
Dobler CC. Dobler CC. Breathe (Sheff). 2018 Dec;14(4):333-335. doi: 10.1183/20734735.026418. Breathe (Sheff). 2018. PMID: 30519302 Free PMC article.
In the IMPACT trial, triple inhalation therapy resulted in a lower rate of moderate or severe COPD exacerbations compared with either dual therapy with ICS/LABA or LAMA/LABA, but pneumonia rates were increased. http://ow.ly/pYJn30mgpFp....
In the IMPACT trial, triple inhalation therapy resulted in a lower rate of moderate or severe COPD exacerbations compared with either dual t …
33 results