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62 results

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Page 1
A large-scale genome-wide association study meta-analysis of cannabis use disorder.
Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, Gudbjartsson DF, Wedow R, Adkins DE, Adkins AE, Alexander J, Bacanu SA, Bigdeli TB, Boden J, Brown SA, Bucholz KK, Bybjerg-Grauholm J, Corley RP, Degenhardt L, Dick DM, Domingue BW, Fox L, Goate AM, Gordon SD, Hack LM, Hancock DB, Hartz SM, Hickie IB, Hougaard DM, Krauter K, Lind PA, McClintick JN, McQueen MB, Meyers JL, Montgomery GW, Mors O, Mortensen PB, Nordentoft M, Pearson JF, Peterson RE, Reynolds MD, Rice JP, Runarsdottir V, Saccone NL, Sherva R, Silberg JL, Tarter RE, Tyrfingsson T, Wall TL, Webb BT, Werge T, Wetherill L, Wright MJ, Zellers S, Adams MJ, Bierut LJ, Boardman JD, Copeland WE, Farrer LA, Foroud TM, Gillespie NA, Grucza RA, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono WG, Johnson EO, Kendler KS, Kennedy MA, Kranzler HR, Madden PAF, Maes HH, Maher BS, Martin NG, McGue M, McIntosh AM, Medland SE, Nelson EC, Porjesz B, Riley BP, Stallings MC, Vanyukov MM, Vrieze S; Psychiatric Genomics Consortium Substance Use Disorders Workgroup; Davis LK, Bogdan R, Gelernter J,… See abstract for full author list ➔ Johnson EC, et al. Lancet Psychiatry. 2020 Dec;7(12):1032-1045. doi: 10.1016/S2215-0366(20)30339-4. Epub 2020 Oct 20. Lancet Psychiatry. 2020. PMID: 33096046 Free PMC article.
FUNDING: National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; National Institute on Drug Abuse; Center for Genomics and Personalized Medicine and the Centre for Integrative Sequencing; The European Commission, Horizon 2020; National Institute o …
FUNDING: National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; National Institute on Drug Abuse; Center f …
Cardiovascular disease/stroke risk stratification in deep learning framework: a review.
Bhagawati M, Paul S, Agarwal S, Protogeron A, Sfikakis PP, Kitas GD, Khanna NN, Ruzsa Z, Sharma AM, Tomazu O, Turk M, Faa G, Tsoulfas G, Laird JR, Rathore V, Johri AM, Viskovic K, Kalra M, Balestrieri A, Nicolaides A, Singh IM, Chaturvedi S, Paraskevas KI, Fouda MM, Saba L, Suri JS. Bhagawati M, et al. Cardiovasc Diagn Ther. 2023 Jun 30;13(3):557-598. doi: 10.21037/cdt-22-438. Epub 2023 Jun 5. Cardiovasc Diagn Ther. 2023. PMID: 37405023 Free PMC article. Review.
The surrogate carotid ultrasound image was mostly used in the UNet-based DL framework for arterial wall segmentation. Ground truth (GT) selection is vital for reducing the risk of bias (RoB) for CVD risk stratification. ...
The surrogate carotid ultrasound image was mostly used in the UNet-based DL framework for arterial wall segmentation. Ground truth (G …
Defining a rob regulon in Escherichia coli by using transposon mutagenesis.
Bennik MH, Pomposiello PJ, Thorne DF, Demple B. Bennik MH, et al. J Bacteriol. 2000 Jul;182(13):3794-801. doi: 10.1128/JB.182.13.3794-3801.2000. J Bacteriol. 2000. PMID: 10850996 Free PMC article.
To determine whether constitutive levels of Rob regulate basal gene expression, we performed a MudJ transposon screen in a rob deletion mutant containing a plasmid that allows for controlled rob gene expression. ...Rob clearly affects the basal express …
To determine whether constitutive levels of Rob regulate basal gene expression, we performed a MudJ transposon screen in a rob …
Discovery of a tyrosine-rich sporocyst wall protein in Eimeria tenella.
Walker RA, Niepceron A, Ramakrishnan C, Sedano L, Hehl AB, Brossier F, Smith NC. Walker RA, et al. Parasit Vectors. 2016 Mar 2;9:124. doi: 10.1186/s13071-016-1410-z. Parasit Vectors. 2016. PMID: 26935317 Free PMC article.
The biochemical basis for sporocyst wall formation is not known. FINDINGS: Here, we report the discovery of a novel tyrosine-rich protein, EtSWP1, in Eimeria tenella. ...We engineered E. tenella to express mCherry-tagged EtSWP1 and showed that the tagged protein localises …
The biochemical basis for sporocyst wall formation is not known. FINDINGS: Here, we report the discovery of a novel tyrosine-rich pro …
Characterization of mycophage endolysin cell wall binding domains targeting Mycobacterium bovis peptidoglycan.
Itterbeek A, Possemiers A, Colak Y, Bäcker LE, Aertsen A, Lavigne R, Paeshuyse J. Itterbeek A, et al. Biochem Biophys Res Commun. 2023 Nov 12;681:291-297. doi: 10.1016/j.bbrc.2023.09.027. Epub 2023 Sep 13. Biochem Biophys Res Commun. 2023. PMID: 37801778
Mostly, they are characterized by a three-module design: an N-terminal peptidase domain, a central catalytic domain and a C-terminal peptidoglycan binding domain. Previously, the affinity of cell wall binding domains (CBDs) to the mycobacterial peptidoglycan layer was show …
Mostly, they are characterized by a three-module design: an N-terminal peptidase domain, a central catalytic domain and a C-terminal peptido …
The diagnostic value of non-invasive methods for diagnosing bladder outlet obstruction in men with lower urinary tract symptoms: A meta-analysis.
Cheng Y, Li T, Wu X, Ling Q, Rao K, Yuan X, Chen Z, Du G, Xu S. Cheng Y, et al. Front Surg. 2022 Sep 20;9:986679. doi: 10.3389/fsurg.2022.986679. eCollection 2022. Front Surg. 2022. PMID: 36338622 Free PMC article. Review.
Retrieved studies were then reviewed for eligibility and data were extracted. The risk of bias (RoB) was assessed using the QUADAS-2 tool. We then performed a formal meta-analysis to evaluate the accuracy of various non-invasive methods for diagnosing BOO in men. RESULTS: …
Retrieved studies were then reviewed for eligibility and data were extracted. The risk of bias (RoB) was assessed using the QUADAS-2 …
Platelet physiology and thrombosis.
Andrews RK, Berndt MC. Andrews RK, et al. Thromb Res. 2004;114(5-6):447-53. doi: 10.1016/j.thromres.2004.07.020. Thromb Res. 2004. PMID: 15507277 Review.
Glycoprotein (GP) Ibalpha of the GPIb-IX-V complex and GPVI bind von Willebrand factor (vWF) and collagen, respectively, and are critical for the initial interaction of circulating platelets with the injured vessel wall under high shear conditions. These interactions act t …
Glycoprotein (GP) Ibalpha of the GPIb-IX-V complex and GPVI bind von Willebrand factor (vWF) and collagen, respectively, and are critical fo …
Efficacy and Safety of Platelet-Rich Plasma Injections for the Treatment of Female Sexual Dysfunction and Stress Urinary Incontinence: A Systematic Review.
Dankova I, Pyrgidis N, Tishukov M, Georgiadou E, Nigdelis MP, Solomayer EF, Marcon J, Stief CG, Hatzichristou D. Dankova I, et al. Biomedicines. 2023 Oct 28;11(11):2919. doi: 10.3390/biomedicines11112919. Biomedicines. 2023. PMID: 38001920 Free PMC article. Review.
After title/abstract and full-text screening, clinical studies on humans evaluating the efficacy of PRP in gynecological disorders using standardized tools were included. Risk of bias was undertaken with RoB-2 for randomized-controlled trials (RCT) and the Newcastle-Ottawa …
After title/abstract and full-text screening, clinical studies on humans evaluating the efficacy of PRP in gynecological disorders using sta …
Is the facial bone wall critical to achieving esthetic outcomes in immediate implant placement with immediate restoration? A systematic review.
Martins SCR, Da Costa Marques M, Gomes Vidal M, Tolentino PHMP, Dinelli RG, De Oliveira Fernandes GV, Shibli JA. Martins SCR, et al. Adv Clin Exp Med. 2024 Jan 5. doi: 10.17219/acem/173573. Online ahead of print. Adv Clin Exp Med. 2024. PMID: 38180330 Review.
The risk of bias was assessed using the ROBINS-I and Modified-Cochrane RoB tools. RESULTS: Twelve studies were included in this systematic review. ...CONCLUSION: It is possible to conclude that esthetic results and increased final PES or patient satisfaction index in IIP t …
The risk of bias was assessed using the ROBINS-I and Modified-Cochrane RoB tools. RESULTS: Twelve studies were included in this syste …
Effects of High-Frequency Chest Wall Oscillation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Huang HP, Chen KH, Tsai CL, Chang WP, Chiu SY, Lin SR, Lin YH. Huang HP, et al. Int J Chron Obstruct Pulmon Dis. 2022 Nov 10;17:2857-2869. doi: 10.2147/COPD.S378642. eCollection 2022. Int J Chron Obstruct Pulmon Dis. 2022. PMID: 36381994 Free PMC article.
PURPOSE: This study aimed to evaluate the efficacy of high-frequency chest wall oscillation for sputum expectoration and hospital length of stay in patients with acute exacerbations of chronic obstructive pulmonary disease. ...The methodological quality of the included stu …
PURPOSE: This study aimed to evaluate the efficacy of high-frequency chest wall oscillation for sputum expectoration and hospital len …
62 results