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Year Number of Results
2017 2
2018 1
2019 1
2020 2
2021 2
2022 2
2023 4
2024 0

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Page 1
Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged acute lymphoblastic leukemia.
Schneider P, Crump NT, Arentsen-Peters STCJM, Smith AL, Hagelaar R, Adriaanse FRS, Bos RS, de Jong A, Nierkens S, Koopmans B, Milne TA, Pieters R, Stam RW. Schneider P, et al. Among authors: hagelaar r. Exp Hematol Oncol. 2023 Sep 22;12(1):81. doi: 10.1186/s40164-023-00445-8. Exp Hematol Oncol. 2023. PMID: 37740239 Free PMC article.
Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia.
Smits WK, Vermeulen C, Hagelaar R, Kimura S, Vroegindeweij EM, Buijs-Gladdines JGCAM, van de Geer E, Verstegen MJAM, Splinter E, van Reijmersdal SV, Buijs A, Galjart N, van Eyndhoven W, van Min M, Kuiper R, Kemmeren P, Mullighan CG, de Laat W, Meijerink JPP. Smits WK, et al. Among authors: hagelaar r. Cell Rep. 2023 Apr 25;42(4):112373. doi: 10.1016/j.celrep.2023.112373. Epub 2023 Apr 14. Cell Rep. 2023. PMID: 37060567 Free PMC article.
Toward on-site food authentication using nanopore sequencing.
Voorhuijzen-Harink MM, Hagelaar R, van Dijk JP, Prins TW, Kok EJ, Staats M. Voorhuijzen-Harink MM, et al. Among authors: hagelaar r. Food Chem X. 2019 Jun 5;2:100035. doi: 10.1016/j.fochx.2019.100035. eCollection 2019 Jun 30. Food Chem X. 2019. PMID: 31432019 Free PMC article.
MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus.
Canté-Barrett K, Meijer MT, Cordo' V, Hagelaar R, Yang W, Yu J, Smits WK, Nulle ME, Jansen JP, Pieters R, Yang JJ, Haigh JJ, Goossens S, Meijerink JP. Canté-Barrett K, et al. Among authors: hagelaar r. JCI Insight. 2022 Jul 8;7(13):e150363. doi: 10.1172/jci.insight.150363. JCI Insight. 2022. PMID: 35536646 Free PMC article.
A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia.
Tottone L, Lancho O, Loh JW, Singh A, Kimura S, Roels J, Kuchmiy A, Strubbe S, Lawlor MA, da Silva-Diz V, Luo S, Gachet S, García-Prieto CA, Hagelaar R, Esteller M, Meijerink JPP, Soulier J, Taghon T, Van Vlierberghe P, Mullighan CG, Khiabanian H, Rocha PP, Herranz D. Tottone L, et al. Among authors: hagelaar r. Blood Cancer Discov. 2021 Jan;2(1):92-109. doi: 10.1158/2643-3230.BCD-20-0201. Epub 2020 Nov 24. Blood Cancer Discov. 2021. PMID: 33458694 Free PMC article.
BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway.
Butler M, van Ingen Schenau DS, Yu J, Jenni S, Dobay MP, Hagelaar R, Vervoort BMT, Tee TM, Hoff FW, Meijerink JP, Kornblau SM, Bornhauser B, Bourquin JP, Kuiper RP, van der Meer LT, van Leeuwen FN. Butler M, et al. Among authors: hagelaar r. Blood. 2021 Dec 9;138(23):2383-2395. doi: 10.1182/blood.2021011787. Blood. 2021. PMID: 34280258 Free PMC article. Clinical Trial.
STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment.
Van der Zwet JCG, Cordo' V, Buijs-Gladdines JGCAM, Hagelaar R, Smits WK, Vroegindeweij E, Graus LTM, Poort V, Nulle M, Pieters R, Meijerink JPP. Van der Zwet JCG, et al. Among authors: hagelaar r. Haematologica. 2023 Mar 1;108(3):732-746. doi: 10.3324/haematol.2021.280405. Haematologica. 2023. PMID: 35734930 Free PMC article.
13 results