Screening Versus Brief Domain-specific Tests to Assess Long-term Postoperative Cognitive Dysfunction After Concomitant Aortic Valve Replacement and Coronary Artery Bypass Grafting

J Cardiovasc Nurs. 2019 Nov/Dec;34(6):511-516. doi: 10.1097/JCN.0000000000000596.

Abstract

Background: Although postoperative cognitive dysfunction is a relevant complication after surgery, assessment for the condition is not routine in clinical practice.

Objective: The aim of this study was to compare the use of screening versus brief domain-specific cognitive tests in assessing long-term cognitive dysfunction after concomitant aortic valve replacement and coronary artery bypass grafting.

Methods: In this observational prospective study, we evaluated 70 patients preoperatively and after 1, 6, and 12 months using 2 screening tests (Mini-Mental State Examination and Clock Drawing Test) and 2 brief domain-specific cognitive tests (Trail Making Test to evaluate attention and executive function, and Semantic and Phonological Tests to evaluate verbal fluency).

Results: The brief domain-specific cognitive tests detected significant postoperative worsening in performances (up to 19% on the Trail Making Test and 15.4% on verbal fluency tests at 6 months). Postoperative mild attention/executive dysfunction or inferior normal performance was detected with the maximums being seen at 6 months (44.6%, P < .001). Performances on screening tests did not significantly change during the study period.

Conclusions: A brief domain-specific cognitive evaluation could be routinely implemented in perioperative care practice to detect postoperative cognitive dysfunction.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Aged
  • Coronary Artery Bypass*
  • Female
  • Heart Valve Prosthesis Implantation*
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Postoperative Cognitive Complications / diagnosis*
  • Prospective Studies
  • Time Factors