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Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs.
Hurler L, Toonen EJM, Kajdácsi E, van Bree B, Brandwijk RJMGE, de Bruin W, Lyons PA, Bergamaschi L; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Sinkovits G, Cervenak L, Würzner R, Prohászka Z. Hurler L, et al. Among authors: brandwijk rjmge. Front Immunol. 2022 Nov 4;13:1039765. doi: 10.3389/fimmu.2022.1039765. eCollection 2022. Front Immunol. 2022. PMID: 36420270 Free PMC article.
Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy.
Thijssen VL, Postel R, Brandwijk RJ, Dings RP, Nesmelova I, Satijn S, Verhofstad N, Nakabeppu Y, Baum LG, Bakkers J, Mayo KH, Poirier F, Griffioen AW. Thijssen VL, et al. Among authors: brandwijk rj. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15975-80. doi: 10.1073/pnas.0603883103. Epub 2006 Oct 16. Proc Natl Acad Sci U S A. 2006. PMID: 17043243 Free PMC article.
Oxidative Stress Increases Endogenous Complement-Dependent Inflammatory and Angiogenic Responses in Retinal Pigment Epithelial Cells Independently of Exogenous Complement Sources.
Trakkides TO, Schäfer N, Reichenthaler M, Kühn K, Brandwijk RJMGE, Toonen EJM, Urban F, Wegener J, Enzmann V, Pauly D. Trakkides TO, et al. Among authors: brandwijk rjmge. Antioxidants (Basel). 2019 Nov 13;8(11):548. doi: 10.3390/antiox8110548. Antioxidants (Basel). 2019. PMID: 31766295 Free PMC article.
Anti-angiogenesis and anti-tumor activity of recombinant anginex.
Brandwijk RJ, Dings RP, van der Linden E, Mayo KH, Thijssen VL, Griffioen AW. Brandwijk RJ, et al. Biochem Biophys Res Commun. 2006 Oct 27;349(3):1073-8. doi: 10.1016/j.bbrc.2006.08.154. Epub 2006 Sep 5. Biochem Biophys Res Commun. 2006. PMID: 16970922