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Year | Number of Results |
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2016 | 3 |
2019 | 1 |
2020 | 1 |
2024 | 0 |
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Page 1
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm.
ACS Chem Biol. 2020 Mar 20;15(3):657-668. doi: 10.1021/acschembio.9b00748. Epub 2020 Feb 21.
ACS Chem Biol. 2020.
PMID: 31990523
Free PMC article.
A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Bauer MR, Jones RN, Tareque RK, Springett B, Dingler FA, Verduci L, Patel KJ, Fersht AR, Joerger AC, Spencer J.
Bauer MR, et al. Among authors: jones rn.
Future Med Chem. 2019 Oct;11(19):2491-2504. doi: 10.4155/fmc-2019-0181.
Future Med Chem. 2019.
PMID: 31633398
Free PMC article.
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Elaboration of tetra-orthogonally-substituted aromatic scaffolds towards novel EGFR-kinase inhibitors.
Close AJ, Jones RN, Ocasio CA, Kemmitt P, Roe SM, Spencer J.
Close AJ, et al. Among authors: jones rn.
Org Biomol Chem. 2016 Sep 21;14(35):8246-52. doi: 10.1039/c6ob01394e. Epub 2016 Jul 25.
Org Biomol Chem. 2016.
PMID: 27453149
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Harnessing Fluorine-Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs.
Bauer MR, Jones RN, Baud MG, Wilcken R, Boeckler FM, Fersht AR, Joerger AC, Spencer J.
Bauer MR, et al. Among authors: jones rn.
ACS Chem Biol. 2016 Aug 19;11(8):2265-74. doi: 10.1021/acschembio.6b00315. Epub 2016 Jun 21.
ACS Chem Biol. 2016.
PMID: 27267810
Free PMC article.
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A synthetic, catalytic and theoretical investigation of an unsymmetrical SCN pincer palladacycle.
Roffe GW, Boonseng S, Baltus CB, Coles SJ, Day IJ, Jones RN, Press NJ, Ruiz M, Tizzard GJ, Cox H, Spencer J.
Roffe GW, et al. Among authors: jones rn.
R Soc Open Sci. 2016 Apr 6;3(4):150656. doi: 10.1098/rsos.150656. eCollection 2016 Apr.
R Soc Open Sci. 2016.
PMID: 27152207
Free PMC article.
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