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Engineering NK-CAR.19 cells with the IL-15/IL-15Rα complex improved proliferation and anti-tumor effect in vivo.
Silvestre RN, Eitler J, de Azevedo JTC, Tirapelle MC, Fantacini DMC, de Souza LEB, Swiech K, Covas DT, Calado RT, Montero PO, Malmegrim KCR, Figueiredo ML, Tonn T, Picanço-Castro V. Silvestre RN, et al. Front Immunol. 2023 Sep 25;14:1226518. doi: 10.3389/fimmu.2023.1226518. eCollection 2023. Front Immunol. 2023. PMID: 37818365 Free PMC article.
Engineering CAR-NK cells: how to tune innate killer cells for cancer immunotherapy.
Schmidt D, Ebrahimabadi S, Gomes KRS, de Moura Aguiar G, Cariati Tirapelle M, Nacasaki Silvestre R, de Azevedo JTC, Tadeu Covas D, Picanço-Castro V. Schmidt D, et al. Among authors: nacasaki silvestre r. Immunother Adv. 2022 Feb 3;2(1):ltac003. doi: 10.1093/immadv/ltac003. eCollection 2022. Immunother Adv. 2022. PMID: 35919494 Free PMC article. Review.
Establishment of a simple and efficient platform for car-t cell generation and expansion: from lentiviral production to in vivo studies.
Picanço-Castro V, Moço PD, Mizukami A, Vaz LD, de Souza Fernandes Pereira M, Silvestre RN, de Azevedo JTC, de Sousa Bomfim A, de Abreu Neto MS, Malmegrim KCR, Swiech K, Covas DT. Picanço-Castro V, et al. Among authors: silvestre rn. Hematol Transfus Cell Ther. 2020 Apr-Jun;42(2):150-158. doi: 10.1016/j.htct.2019.06.007. Epub 2019 Oct 9. Hematol Transfus Cell Ther. 2020. PMID: 31676276 Free PMC article.