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Effect of aromatherapy on patients with Alzheimer's disease.
Jimbo D, Kimura Y, Taniguchi M, Inoue M, Urakami K. Jimbo D, et al. Psychogeriatrics. 2009 Dec;9(4):173-9. doi: 10.1111/j.1479-8301.2009.00299.x. Psychogeriatrics. 2009. PMID: 20377818 Free article. Clinical Trial.
To determine the effects of aromatherapy, patients were evaluated using the Japanese version of the Gottfries, Brane, Steen scale (GBSS-J), Functional Assessment Staging of Alzheimer's disease (FAST), a revised version of Hasegawa's Dementia Scale (HDS-R), and the Touch Pa …
To determine the effects of aromatherapy, patients were evaluated using the Japanese version of the Gottfries, Brane, Steen scale (GBSS-J), …
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury.
Tsuda M, Shigemoto-Mogami Y, Koizumi S, Mizokoshi A, Kohsaka S, Salter MW, Inoue K. Tsuda M, et al. Nature. 2003 Aug 14;424(6950):778-83. doi: 10.1038/nature01786. Nature. 2003. PMID: 12917686 Free article.
Taken together, our results demonstrate that activation of P2X4Rs in hyperactive microglia is necessary for tactile allodynia after nerve injury and is sufficient to produce tactile allodynia in normal animals. Thus, blocking P2X4Rs in microglia might be a new therapeutic …
Taken together, our results demonstrate that activation of P2X4Rs in hyperactive microglia is necessary for tactile allodynia after nerve in …
Systemic administration of resveratrol suppress the nociceptive neuronal activity of spinal trigeminal nucleus caudalis in rats.
Takehana S, Sekiguchi K, Inoue M, Kubota Y, Ito Y, Yui K, Shimazu Y, Takeda M. Takehana S, et al. Brain Res Bull. 2016 Jan;120:117-22. doi: 10.1016/j.brainresbull.2015.11.011. Epub 2015 Nov 28. Brain Res Bull. 2016. PMID: 26608254 Free article.
These results suggest that, in the absence of inflammatory or neuropathic pain, acute intravenous resveratrol administration suppresses trigeminal sensory transmission, including nociception, and so resveratrol may be used as a complementary and alternative medicine therapeuti …
These results suggest that, in the absence of inflammatory or neuropathic pain, acute intravenous resveratrol administration suppresses trig …
Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.
Hasegawa S, Kohro Y, Shiratori M, Ishii S, Shimizu T, Tsuda M, Inoue K. Hasegawa S, et al. PLoS One. 2010 May 3;5(5):e10467. doi: 10.1371/journal.pone.0010467. PLoS One. 2010. PMID: 20454616 Free PMC article.
CONCLUSIONS: Our results indicate that the PAF/PAFR system has an important role in production of TNFalpha and IL-1beta in the DRG and tactile allodynia following peripheral nerve injury and suggest that blocking PAFRs may be a viable therapeutic strategy for treating neur …
CONCLUSIONS: Our results indicate that the PAF/PAFR system has an important role in production of TNFalpha and IL-1beta in the DRG and tacti …
FK960 [N-(4-acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate], a novel potential antidementia drug, restores the regional cerebral blood flow response abolished by scopolamine but not by HA-966: a positron emission tomography study with unanesthetized rhesus monkeys.
Tsukada H, Yamazaki S, Noda A, Inoue T, Matsuoka N, Kakiuchi T, Nishiyama S, Nishimura S. Tsukada H, et al. Brain Res. 1999 Jun 19;832(1-2):118-23. doi: 10.1016/s0006-8993(99)01465-1. Brain Res. 1999. PMID: 10375657