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Page 1
Structural insight into apelin receptor-G protein stoichiometry.
Yue Y, Liu L, Wu LJ, Wu Y, Wang L, Li F, Liu J, Han GW, Chen B, Lin X, Brouillette RL, Breault É, Longpré JM, Shi S, Lei H, Sarret P, Stevens RC, Hanson MA, Xu F. Yue Y, et al. Among authors: brouillette rl. Nat Struct Mol Biol. 2022 Jul;29(7):688-697. doi: 10.1038/s41594-022-00797-5. Epub 2022 Jul 11. Nat Struct Mol Biol. 2022. PMID: 35817871
In Search of the Optimal Macrocyclization Site for Neurotensin.
Sousbie M, Besserer-Offroy É, Brouillette RL, Longpré JM, Leduc R, Sarret P, Marsault É. Sousbie M, et al. Among authors: brouillette rl. ACS Med Chem Lett. 2018 Jan 29;9(3):227-232. doi: 10.1021/acsmedchemlett.7b00500. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541365 Free PMC article.
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Gusach A, Luginina A, Marin E, Brouillette RL, Besserer-Offroy É, Longpré JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, Kovalev K, Shevtsov M, Gordeliy V, Han GW, Katritch V, Borshchevskiy V, Sarret P, Mishin A, Cherezov V. Gusach A, et al. Among authors: brouillette rl. Nat Commun. 2019 Dec 6;10(1):5573. doi: 10.1038/s41467-019-13348-2. Nat Commun. 2019. PMID: 31811124 Free PMC article.
The signaling signature of the neurotensin type 1 receptor with endogenous ligands.
Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R. Besserer-Offroy É, et al. Among authors: brouillette rl. Eur J Pharmacol. 2017 Jun 15;805:1-13. doi: 10.1016/j.ejphar.2017.03.046. Epub 2017 Mar 22. Eur J Pharmacol. 2017. PMID: 28341345
Data set describing the in vitro biological activity of JMV2009, a novel silylated neurotensin(8-13) analog.
Besserer-Offroy É, Tétreault P, Brouillette RL, René A, Murza A, Fanelli R, Kirby K, Parent A, Dubuc I, Beaudet N, Côté J, Longpré JM, Martinez J, Cavelier F, Sarret P. Besserer-Offroy É, et al. Among authors: brouillette rl. Data Brief. 2020 Jun 20;31:105884. doi: 10.1016/j.dib.2020.105884. eCollection 2020 Aug. Data Brief. 2020. PMID: 32637491 Free PMC article.
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog.
Tétreault P, Besserer-Offroy É, Brouillette RL, René A, Murza A, Fanelli R, Kirby K, Parent AJ, Dubuc I, Beaudet N, Côté J, Longpré JM, Martinez J, Cavelier F, Sarret P. Tétreault P, et al. Among authors: brouillette rl. Eur J Pharmacol. 2020 Sep 5;882:173174. doi: 10.1016/j.ejphar.2020.173174. Epub 2020 Jun 10. Eur J Pharmacol. 2020. PMID: 32534076