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Page 1
Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair.
Kovatcheva M, Melendez E, Chondronasiou D, Pietrocola F, Bernad R, Caballe A, Junza A, Capellades J, Holguín-Horcajo A, Prats N, Durand S, Rovira M, Yanes O, Stephan-Otto Attolini C, Kroemer G, Serrano M. Kovatcheva M, et al. Among authors: bernad r. Nat Metab. 2023 Nov;5(11):1911-1930. doi: 10.1038/s42255-023-00916-6. Epub 2023 Nov 16. Nat Metab. 2023. PMID: 37973897 Free PMC article.
Manipulating the Mediator complex to induce naïve pluripotency.
Lynch CJ, Bernad R, Calvo I, Serrano M. Lynch CJ, et al. Among authors: bernad r. Exp Cell Res. 2020 Oct 15;395(2):112215. doi: 10.1016/j.yexcr.2020.112215. Epub 2020 Aug 6. Exp Cell Res. 2020. PMID: 32771524 Free PMC article. Review.
Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems.
Peschke K, Jakubowsky H, Schäfer A, Maurer C, Lange S, Orben F, Bernad R, Harder FN, Eiber M, Öllinger R, Steiger K, Schlitter M, Weichert W, Mayr U, Phillip V, Schlag C, Schmid RM, Braren RF, Kong B, Demir IE, Friess H, Rad R, Saur D, Schneider G, Reichert M. Peschke K, et al. Among authors: bernad r. EMBO Mol Med. 2022 Apr 7;14(4):e14876. doi: 10.15252/emmm.202114876. Epub 2022 Feb 4. EMBO Mol Med. 2022. PMID: 35119792 Free PMC article.
The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.
Lynch CJ, Bernad R, Calvo I, Nóbrega-Pereira S, Ruiz S, Ibarz N, Martinez-Val A, Graña-Castro O, Gómez-López G, Andrés-León E, Espinosa Angarica V, Del Sol A, Ortega S, Fernandez-Capetillo O, Rojo E, Munoz J, Serrano M. Lynch CJ, et al. Among authors: bernad r. Cell Rep. 2018 Jan 9;22(2):396-410. doi: 10.1016/j.celrep.2017.12.062. Cell Rep. 2018. PMID: 29320736 Free PMC article.
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.
Lynch CJ, Bernad R, Martínez-Val A, Shahbazi MN, Nóbrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Ginés L, Alcazar N, Graña-Castro O, Gómez-Lopez G, Aksoy I, Muñoz-Martín M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Muñoz J, Zernicka-Goetz M, Serrano M. Lynch CJ, et al. Among authors: bernad r. Nat Cell Biol. 2020 Oct;22(10):1223-1238. doi: 10.1038/s41556-020-0573-1. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989249 Free article.
Polμ deficiency increases resistance to oxidative damage and delays liver aging.
Escudero B, Lucas D, Albo C, Dhup S, Bacher JW, Sánchez-Muñoz A, Fernández M, Rivera-Torres J, Carmona RM, Fuster E, Carreiro C, Bernad R, González MA, Andrés V, Blanco L, Roche E, Fabregat I, Samper E, Bernad A. Escudero B, et al. Among authors: bernad r. PLoS One. 2014 Apr 1;9(4):e93074. doi: 10.1371/journal.pone.0093074. eCollection 2014. PLoS One. 2014. PMID: 24691161 Free PMC article.