Facile Iodine-Catalyzed Michael Addition of Indoles to α,α'-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones

Rammohan Pal; Arpita Das Gupta; Asok K Mallik

doi:10.5402/2012/674629

Facile Iodine-Catalyzed Michael Addition of Indoles to α,α'-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones

ISRN Org Chem. 2012 Nov 5:2012:674629. doi: 10.5402/2012/674629. eCollection 2012.

Authors

Rammohan Pal¹, Arpita Das Gupta, Asok K Mallik

Affiliation

¹ Department of Chemistry, Acharya Jagadish Chandra Bose College, Kolkata 700 020, West Bengal, India.

Abstract

Iodine-catalyzed reaction of indoles with α,α'-bis(arylmethylene)cyclopentanones afforded one diastereomer of the corresponding Michael adducts, namely, E-2-(3-indolylphenylmethyl)-5-phenylmethylenecyclopentanones, in a good yield. The products form a new group of indole derivatives.