Rajesh Gumpena - Search Results

Year	Number of Results
2011	1
2012	1
2013	1
2014	1
2015	2
2017	1
2018	3
2019	1
2021	2
2024	0

1

Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria.

Ding J, Gumpena R, Boily MO, Caron A, Chong O, Cox JH, Dumais V, Gaudreault S, Graff AH, King A, Knight J, Oballa R, Surendradoss J, Tang T, Wu J, Lowther WT, Powell DA. Ding J, et al. Among authors: gumpena r. ACS Med Chem Lett. 2021 May 20;12(7):1116-1123. doi: 10.1021/acsmedchemlett.1c00196. eCollection 2021 Jul 8. ACS Med Chem Lett. 2021. PMID: 34267881 Free PMC article.

2

Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State.

Forshaw TE, Reisz JA, Nelson KJ, Gumpena R, Lawson JR, Jönsson TJ, Wu H, Clodfelter JE, Johnson LC, Furdui CM, Lowther WT. Forshaw TE, et al. Among authors: gumpena r. Antioxidants (Basel). 2021 Jun 11;10(6):946. doi: 10.3390/antiox10060946. Antioxidants (Basel). 2021. PMID: 34208049 Free PMC article.

3

Crystal structure of the human dual specificity phosphatase 1 catalytic domain.

Gumpena R, Lountos GT, Raran-Kurussi S, Tropea JE, Cherry S, Waugh DS. Gumpena R, et al. Protein Sci. 2018 Feb;27(2):561-567. doi: 10.1002/pro.3328. Epub 2017 Nov 21. Protein Sci. 2018. PMID: 29052270 Free PMC article.

4

MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.

Gumpena R, Lountos GT, Waugh DS. Gumpena R, et al. Acta Crystallogr F Struct Biol Commun. 2018 Sep 1;74(Pt 9):549-557. doi: 10.1107/S2053230X18009901. Epub 2018 Aug 29. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 30198887 Free PMC article.

5

Crystal structure of UDP-glucose pyrophosphorylase from Yersinia pestis, a potential therapeutic target against plague.

Gibbs ME, Lountos GT, Gumpena R, Waugh DS. Gibbs ME, et al. Among authors: gumpena r. Acta Crystallogr F Struct Biol Commun. 2019 Sep 1;75(Pt 9):608-615. doi: 10.1107/S2053230X19011154. Epub 2019 Aug 28. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 31475928 Free PMC article.

6

Identification, biochemical and structural evaluation of species-specific inhibitors against type I methionine aminopeptidases.

Kishor C, Arya T, Reddi R, Chen X, Saddanapu V, Marapaka AK, Gumpena R, Ma D, Liu JO, Addlagatta A. Kishor C, et al. Among authors: gumpena r. J Med Chem. 2013 Jul 11;56(13):5295-305. doi: 10.1021/jm400395p. Epub 2013 Jun 27. J Med Chem. 2013. PMID: 23767698

7

Identification of the molecular basis of inhibitor selectivity between the human and streptococcal type I methionine aminopeptidases.

Arya T, Reddi R, Kishor C, Ganji RJ, Bhukya S, Gumpena R, McGowan S, Drag M, Addlagatta A. Arya T, et al. Among authors: gumpena r. J Med Chem. 2015 Mar 12;58(5):2350-7. doi: 10.1021/jm501790e. Epub 2015 Feb 27. J Med Chem. 2015. PMID: 25699713

8

Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents.

Reddi R, Arya T, Kishor C, Gumpena R, Ganji RJ, Bhukya S, Addlagatta A. Reddi R, et al. Among authors: gumpena r. FEBS J. 2014 Sep;281(18):4240-8. doi: 10.1111/febs.12847. Epub 2014 Jun 6. FEBS J. 2014. PMID: 24841365 Free article.

9

Discovery, Structural and Biochemical Studies of a rare Glu/Asp Specific M1 Class Aminopeptidase from Legionella pneumophila.

Marapaka AK, Pillalamarri V, Gumpena R, Haque N, Bala SC, Jangam A, Addlagatta A. Marapaka AK, et al. Among authors: gumpena r. Int J Biol Macromol. 2018 Dec;120(Pt A):1111-1118. doi: 10.1016/j.ijbiomac.2018.08.172. Epub 2018 Aug 30. Int J Biol Macromol. 2018. PMID: 30172821

10

Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N.

Ganji RJ, Reddi R, Gumpena R, Marapaka AK, Arya T, Sankoju P, Bhukya S, Addlagatta A. Ganji RJ, et al. Among authors: gumpena r. Protein Sci. 2015 May;24(5):823-31. doi: 10.1002/pro.2653. Epub 2015 Apr 8. Protein Sci. 2015. PMID: 25644575 Free PMC article.

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