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New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.
Filimonov AS, Chepanova AA, Luzina OA, Zakharenko AL, Zakharova OD, Ilina ES, Dyrkheeva NS, Kuprushkin MS, Kolotaev AV, Khachatryan DS, Patel J, Leung IKH, Chand R, Ayine-Tora DM, Reynisson J, Volcho KP, Salakhutdinov NF, Lavrik OI. Filimonov AS, et al. Among authors: chand r. Molecules. 2019 Oct 15;24(20):3711. doi: 10.3390/molecules24203711. Molecules. 2019. PMID: 31619021 Free PMC article.
Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments.
Mozhaitsev ES, Zakharenko AL, Suslov EV, Korchagina DV, Zakharova OD, Vasil'eva IA, Chepanova AA, Black E, Patel J, Chand R, Reynisson J, Leung IKH, Volcho KP, Salakhutdinov NF, Lavrik OI. Mozhaitsev ES, et al. Among authors: chand r. Anticancer Agents Med Chem. 2019;19(4):463-472. doi: 10.2174/1871520619666181207094243. Anticancer Agents Med Chem. 2019. PMID: 30523770
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1.
Il'ina IV, Dyrkheeva NS, Zakharenko AL, Sidorenko AY, Li-Zhulanov NS, Korchagina DV, Chand R, Ayine-Tora DM, Chepanova AA, Zakharova OD, Ilina ES, Reynisson J, Malakhova AA, Medvedev SP, Zakian SM, Volcho KP, Salakhutdinov NF, Lavrik OI. Il'ina IV, et al. Among authors: chand r. Molecules. 2020 Jul 31;25(15):3496. doi: 10.3390/molecules25153496. Molecules. 2020. PMID: 32751997 Free PMC article.
Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.
Khomenko TM, Zakharenko AL, Chepanova AA, Ilina ES, Zakharova OD, Kaledin VI, Nikolin VP, Popova NA, Korchagina DV, Reynisson J, Chand R, Ayine-Tora DM, Patel J, Leung IKH, Volcho KP, Salakhutdinov NF, Lavrik OI. Khomenko TM, et al. Among authors: chand r. Int J Mol Sci. 2019 Dec 23;21(1):126. doi: 10.3390/ijms21010126. Int J Mol Sci. 2019. PMID: 31878088 Free PMC article.