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Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model.
Vidal E, Sánchez-Martín MA, Eraña H, Lázaro SP, Pérez-Castro MA, Otero A, Charco JM, Marín B, López-Moreno R, Díaz-Domínguez CM, Geijo M, Ordóñez M, Cantero G, di Bari M, Lorenzo NL, Pirisinu L, d'Agostino C, Torres JM, Béringue V, Telling G, Badiola JJ, Pumarola M, Bolea R, Nonno R, Requena JR, Castilla J. Vidal E, et al. Among authors: lopez moreno r. Acta Neuropathol Commun. 2022 Dec 13;10(1):179. doi: 10.1186/s40478-022-01477-7. Acta Neuropathol Commun. 2022. PMID: 36514160 Free PMC article.
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.
Eraña H, Díaz-Domínguez CM, Charco JM, Vidal E, González-Miranda E, Pérez-Castro MA, Piñeiro P, López-Moreno R, Sampedro-Torres-Quevedo C, Fernández-Veiga L, Tasis-Galarza J, Lorenzo NL, Santini-Santiago A, Lázaro M, García-Martínez S, Gonçalves-Anjo N, San-Juan-Ansoleaga M, Galarza-Ahumada J, Fernández-Muñoz E, Giler S, Valle M, Telling GC, Geijó M, Requena JR, Castilla J. Eraña H, et al. Among authors: lopez moreno r. Acta Neuropathol Commun. 2023 Sep 7;11(1):145. doi: 10.1186/s40478-023-01640-8. Acta Neuropathol Commun. 2023. PMID: 37679832 Free PMC article.
Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases.
Eraña H, Charco JM, González-Miranda E, García-Martínez S, López-Moreno R, Pérez-Castro MA, Díaz-Domínguez CM, García-Salvador A, Castilla J. Eraña H, et al. Among authors: lopez moreno r. Biomolecules. 2020 Mar 19;10(3):469. doi: 10.3390/biom10030469. Biomolecules. 2020. PMID: 32204429 Free PMC article. Review.
Cofactors influence the biological properties of infectious recombinant prions.
Fernández-Borges N, Di Bari MA, Eraña H, Sánchez-Martín M, Pirisinu L, Parra B, Elezgarai SR, Vanni I, López-Moreno R, Vaccari G, Venegas V, Charco JM, Gil D, Harrathi C, D'Agostino C, Agrimi U, Mayoral T, Requena JR, Nonno R, Castilla J. Fernández-Borges N, et al. Among authors: lopez moreno r. Acta Neuropathol. 2018 Feb;135(2):179-199. doi: 10.1007/s00401-017-1782-y. Epub 2017 Nov 1. Acta Neuropathol. 2018. PMID: 29094186
Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies.
Eraña H, Charco JM, Di Bari MA, Díaz-Domínguez CM, López-Moreno R, Vidal E, González-Miranda E, Pérez-Castro MA, García-Martínez S, Bravo S, Fernández-Borges N, Geijo M, D'Agostino C, Garrido J, Bian J, König A, Uluca-Yazgi B, Sabate R, Khaychuk V, Vanni I, Telling GC, Heise H, Nonno R, Requena JR, Castilla J. Eraña H, et al. Among authors: lopez moreno r. PLoS Pathog. 2019 Oct 23;15(10):e1008117. doi: 10.1371/journal.ppat.1008117. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31644574 Free PMC article.