Radek Indra - Search Results

Year	Number of Results
2012	1
2013	1
2014	2
2015	1
2016	6
2017	2
2018	3
2019	6
2020	2
2021	3
2022	1
2024	0

1

The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib.

Vavrová K, Indra R, Pompach P, Heger Z, Hodek P. Vavrová K, et al. Among authors: indra r. Biomed Pharmacother. 2022 Jan;145:112391. doi: 10.1016/j.biopha.2021.112391. Epub 2021 Nov 27. Biomed Pharmacother. 2022. PMID: 34847475 Free article.

2

Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells.

Indra R, Černá T, Heger Z, Hraběta J, Wilhelm M, Dostálová S, Lengálová A, Martínková M, Adam V, Eckschlager T, Schmeiser HH, Arlt VM, Stiborová M. Indra R, et al. Toxicology. 2019 May 1;419:40-54. doi: 10.1016/j.tox.2019.03.009. Epub 2019 Mar 23. Toxicology. 2019. PMID: 30914192

3

Apoferritin/Vandetanib Association Is Long-Term Stable But Does Not Improve Pharmacological Properties of Vandetanib.

Jáklová K, Feglarová T, Rex S, Heger Z, Eckschlager T, Hraběta J, Hodek P, Kolárik M, Indra R. Jáklová K, et al. Among authors: indra r. Int J Mol Sci. 2021 Apr 20;22(8):4250. doi: 10.3390/ijms22084250. Int J Mol Sci. 2021. PMID: 33923880 Free PMC article.

4

Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers.

Baker SC, Arlt VM, Indra R, Joel M, Stiborová M, Eardley I, Ahmad N, Otto W, Burger M, Rubenwolf P, Phillips DH, Southgate J. Baker SC, et al. Among authors: indra r. Mol Carcinog. 2018 May;57(5):606-618. doi: 10.1002/mc.22784. Epub 2018 Feb 1. Mol Carcinog. 2018. PMID: 29323757 Free PMC article.

5

Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes.

Dračínská H, Indra R, Jelínková S, Černá V, Arlt VM, Stiborová M. Dračínská H, et al. Among authors: indra r. Int J Mol Sci. 2021 Jul 28;22(15):8062. doi: 10.3390/ijms22158062. Int J Mol Sci. 2021. PMID: 34360828 Free PMC article.

6

The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro.

Sborchia M, De Prez EG, Antoine MH, Bienfait L, Indra R, Valbuena G, Phillips DH, Nortier JL, Stiborová M, Keun HC, Arlt VM. Sborchia M, et al. Among authors: indra r. Arch Toxicol. 2019 Nov;93(11):3345-3366. doi: 10.1007/s00204-019-02578-4. Epub 2019 Oct 10. Arch Toxicol. 2019. PMID: 31602497 Free PMC article.

7

The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers.

Šulc M, Indra R, Moserová M, Schmeiser HH, Frei E, Arlt VM, Stiborová M. Šulc M, et al. Among authors: indra r. Environ Mol Mutagen. 2016 Apr;57(3):229-35. doi: 10.1002/em.22001. Epub 2016 Feb 26. Environ Mol Mutagen. 2016. PMID: 26919089 Free PMC article.

8

Application of hepatic cytochrome b₅/P450 reductase null (HBRN) mice to study the role of cytochrome b₅ in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine.

Reed L, Indra R, Mrizova I, Moserova M, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM. Reed L, et al. Among authors: indra r. Toxicol Appl Pharmacol. 2019 Mar 1;366:64-74. doi: 10.1016/j.taap.2019.01.020. Epub 2019 Jan 25. Toxicol Appl Pharmacol. 2019. PMID: 30685480 Free PMC article.

9

Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems.

Indra R, Pompach P, Vavrová K, Jáklová K, Heger Z, Adam V, Eckschlager T, Kopečková K, Arlt VM, Stiborová M. Indra R, et al. Environ Toxicol Pharmacol. 2020 Feb;74:103310. doi: 10.1016/j.etap.2019.103310. Epub 2019 Dec 3. Environ Toxicol Pharmacol. 2020. PMID: 31837525

10

Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation.

Indra R, Pompach P, Martínek V, Takácsová P, Vavrová K, Heger Z, Adam V, Eckschlager T, Kopečková K, Arlt VM, Stiborová M. Indra R, et al. Int J Mol Sci. 2019 Jul 10;20(14):3392. doi: 10.3390/ijms20143392. Int J Mol Sci. 2019. PMID: 31295928 Free PMC article.

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