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Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson's disease GBA-N370S dopamine neurons.
Cell Rep. 2023 Mar 28;42(3):112180. doi: 10.1016/j.celrep.2023.112180. Epub 2023 Mar 3.
Cell Rep. 2023.
PMID: 36870058
Free article.
Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models.
Williamson MG, Madureira M, McGuinness W, Heon-Roberts R, Mock ED, Naidoo K, Cramb KML, Caiazza MC, Malpartida AB, Lavelle M, Savory K, Humble SW, Patterson R, Davis JB, Connor-Robson N, Ryan BJ, Wade-Martins R.
Williamson MG, et al. Among authors: heon roberts r.
Hum Mol Genet. 2023 Sep 5;32(18):2808-2821. doi: 10.1093/hmg/ddad102.
Hum Mol Genet. 2023.
PMID: 37384414
Free PMC article.
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CRISPRi: a way to integrate iPSC-derived neuronal models.
Franks SNJ, Heon-Roberts R, Ryan BJ.
Franks SNJ, et al. Among authors: heon roberts r.
Biochem Soc Trans. 2024 Apr 24;52(2):539-551. doi: 10.1042/BST20230190.
Biochem Soc Trans. 2024.
PMID: 38526223
Review.
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Molecular Bases of Neurodegeneration and Cognitive Decline, the Major Burden of Sanfilippo Disease.
Heon-Roberts R, Nguyen ALA, Pshezhetsky AV.
Heon-Roberts R, et al.
J Clin Med. 2020 Jan 27;9(2):344. doi: 10.3390/jcm9020344.
J Clin Med. 2020.
PMID: 32012694
Free PMC article.
Review.
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Selective Inhibitors of Human Neuraminidase 1 (NEU1).
Guo T, Héon-Roberts R, Zou C, Zheng R, Pshezhetsky AV, Cairo CW.
Guo T, et al. Among authors: heon roberts r.
J Med Chem. 2018 Dec 27;61(24):11261-11279. doi: 10.1021/acs.jmedchem.8b01411. Epub 2018 Dec 5.
J Med Chem. 2018.
PMID: 30457869
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Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT.
Pan X, Taherzadeh M, Bose P, Heon-Roberts R, Nguyen ALA, Xu T, Pará C, Yamanaka Y, Priestman DA, Platt FM, Khan S, Fnu N, Tomatsu S, Morales CR, Pshezhetsky AV.
Pan X, et al. Among authors: heon roberts r.
J Exp Med. 2022 Aug 1;219(8):e20211860. doi: 10.1084/jem.20211860. Epub 2022 Jun 15.
J Exp Med. 2022.
PMID: 35704026
Free PMC article.
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Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism.
Okarmus J, Havelund JF, Ryding M, Schmidt SI, Bogetofte H, Heon-Roberts R, Wade-Martins R, Cowley SA, Ryan BJ, Færgeman NJ, Hyttel P, Meyer M.
Okarmus J, et al. Among authors: heon roberts r.
Stem Cell Reports. 2021 Jun 8;16(6):1510-1526. doi: 10.1016/j.stemcr.2021.04.022. Epub 2021 May 27.
Stem Cell Reports. 2021.
PMID: 34048689
Free PMC article.
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