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Evaluation of the gut microbiota after metformin intervention in children with obesity: A metagenomic study of a randomized controlled trial.
Pastor-Villaescusa B, Plaza-Díaz J, Egea-Zorrilla A, Leis R, Bueno G, Hoyos R, Vázquez-Cobela R, Latorre M, Cañete MD, Caballero-Villarraso J, Gil Á, Cañete R, Aguilera CM. Pastor-Villaescusa B, et al. Among authors: hoyos r. Biomed Pharmacother. 2021 Feb;134:111117. doi: 10.1016/j.biopha.2020.111117. Epub 2020 Dec 24. Biomed Pharmacother. 2021. PMID: 33360047 Free article. Clinical Trial.
Metformin for Obesity in Prepubertal and Pubertal Children: A Randomized Controlled Trial.
Pastor-Villaescusa B, Cañete MD, Caballero-Villarraso J, Hoyos R, Latorre M, Vázquez-Cobela R, Plaza-Díaz J, Maldonado J, Bueno G, Leis R, Gil Á, Cañete R, Aguilera CM. Pastor-Villaescusa B, et al. Among authors: hoyos r. Pediatrics. 2017 Jul;140(1):e20164285. doi: 10.1542/peds.2016-4285. Epub 2017 Jun 12. Pediatrics. 2017. PMID: 28759403 Free article. Clinical Trial.
Common Variants in 22 Genes Regulate Response to Metformin Intervention in Children with Obesity: A Pharmacogenetic Study of a Randomized Controlled Trial.
Anguita-Ruiz A, Pastor-Villaescusa B, Leis R, Bueno G, Hoyos R, Vázquez-Cobela R, Latorre-Millán M, Cañete MD, Caballero-Villarraso J, Gil Á, Cañete R, Aguilera CM. Anguita-Ruiz A, et al. Among authors: hoyos r. J Clin Med. 2019 Sep 16;8(9):1471. doi: 10.3390/jcm8091471. J Clin Med. 2019. PMID: 31527397 Free PMC article.
Evaluation of differential effects of metformin treatment in obese children according to pubertal stage and genetic variations: study protocol for a randomized controlled trial.
Pastor-Villaescusa B, Caballero-Villarraso J, Cañete MD, Hoyos R, Maldonado J, Bueno G, Leis R, Gil Á, Cañete R, Aguilera CM. Pastor-Villaescusa B, et al. Among authors: hoyos r. Trials. 2016 Jul 18;17(1):323. doi: 10.1186/s13063-016-1403-4. Trials. 2016. PMID: 27432166 Free PMC article. Clinical Trial.