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The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer.
Nelczyk AT, Ma L, Gupta AD, Gamage HEV, McHenry MT, Henn MA, Kadiri M, Wang Y, Krawczynska N, Bendre S, He S, Shahoei SH, Madak-Erdogan Z, Hsiao SH, Saleh T, Carpenter V, Gewirtz DA, Spinella MJ, Nelson ER. Nelczyk AT, et al. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1;1868(11):166515. doi: 10.1016/j.bbadis.2022.166515. Epub 2022 Aug 4. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35932893 Free PMC article.
Synthesis and Preclinical Evaluation of Novel (68)Ga-Labeled (R)-Pyrrolidin-2-yl-boronic Acid-Based PET Tracers for Fibroblast Activation Protein-Targeted Cancer Imaging.
Bendre S, Kuo HT, Merkens H, Zhang Z, Wong AAWL, Bénard F, Lin KS. Bendre S, et al. Pharmaceuticals (Basel). 2023 May 28;16(6):798. doi: 10.3390/ph16060798. Pharmaceuticals (Basel). 2023. PMID: 37375746 Free PMC article.
Fibroblast activation protein (FAP) is a membrane-tethered serine protease overexpressed in the reactive stromal fibroblasts of >90% human carcinomas, which makes it a promising target for developing radiopharmaceuticals for the imaging and therapy of carcinomas. Here, we synt …
Fibroblast activation protein (FAP) is a membrane-tethered serine protease overexpressed in the reactive stromal fibroblasts of >90% huma …
A Study of Triplet-Primed PCR for Identification of CAG Repeat Expansion in the HTT Gene in a Cohort of 503 Indian Cases with Huntington's Disease Symptoms.
Chheda P, Chanekar M, Salunkhe Y, Dama T, Pais A, Pande S, Bendre R, Shah N. Chheda P, et al. Mol Diagn Ther. 2018 Jun;22(3):353-359. doi: 10.1007/s40291-018-0327-y. Mol Diagn Ther. 2018. PMID: 29619771

BACKGROUND: Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder with an average age at onset of 40 years. ...There were seven juvenile cases with an age of onset of < 20 years, with the longest allele comprising 106 CAG repeats found in an 8-ye

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BACKGROUND: Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder with an average age at onset of 40 years. . …