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Enterobacterales high-risk clones and plasmids spreading blaESBL/AmpC and blaOXA-48 genes within and between hospitalized dogs and their environment.
Haenni M, Boulouis HJ, Lagrée AC, Drapeau A, Va F, Billet M, Châtre P, Madec JY. Haenni M, et al. J Antimicrob Chemother. 2022 Sep 30;77(10):2754-2762. doi: 10.1093/jac/dkac268. J Antimicrob Chemother. 2022. PMID: 35983589
BACKGROUND: Compared with healthcare settings, the role of veterinary hospitals in the spread of extended-spectrum cephalosporin- and carbapenem-resistant (ESC-R/CP-R) bacteria has been overlooked. OBJECTIVES: To investigate using genome-based approaches the dynamic …
BACKGROUND: Compared with healthcare settings, the role of veterinary hospitals in the spread of extended-spectrum cephalosporin- and carbap …
Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America.
Zamudio R, Boerlin P, Beyrouthy R, Madec JY, Schwarz S, Mulvey MR, Zhanel GG, Cormier A, Chalmers G, Bonnet R, Haenni M, Eichhorn I, Kaspar H, Garcia-Fierro R, Wood JLN, Mather AE. Zamudio R, et al. Nat Commun. 2022 Dec 12;13(1):7490. doi: 10.1038/s41467-022-34970-7. Nat Commun. 2022. PMID: 36509735 Free PMC article.
Extended-spectrum cephalosporins (ESCs) are critically important antimicrobial agents for human and veterinary medicine. ESC resistance (ESC-R) genes have spread worldwide through plasmids and clonal expansion, yet the distribution and dynamics of ESC-R genes in dif …
Extended-spectrum cephalosporins (ESCs) are critically important antimicrobial agents for human and veterinary medicine. ESC resistance (ESC …
Platelet Counts and Liver Enzymes After Gastric Bypass Surgery.
Johansson HE, Wåhlén A, Aldenbäck E, Haenni A. Johansson HE, et al. Obes Surg. 2018 Jun;28(6):1526-1531. doi: 10.1007/s11695-017-3035-5. Obes Surg. 2018. PMID: 29222767 Free PMC article. Clinical Trial.

CRP was lowered from 7.3 to 5.4 mg/l p < 0.001 and ferritin from 106 to 84 mug/l p < 0.001. The alterations in PCs correlated with the changes in CRP (r = 0.38, p = 0.001), BMI (r = 0.25, p = 0.012), weight (r = 0.24, p = 0.015) and inversely correlated

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CRP was lowered from 7.3 to 5.4 mg/l p < 0.001 and ferritin from 106 to 84 mug/l p < 0.001. The alterations in PCs correlated with the

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High Genetic Diversity of Enterobacteriaceae Clones and Plasmids Disseminating Resistance to Extended-Spectrum Cephalosporins and Colistin in Healthy Chicken in Tunisia.
Saidani M, Messadi L, Chaouechi A, Tabib I, Saras E, Soudani A, Daaloul-Jedidi M, Mamlouk A, Ben Chehida F, Chakroun C, Madec JY, Haenni M. Saidani M, et al. Microb Drug Resist. 2019 Dec;25(10):1507-1513. doi: 10.1089/mdr.2019.0138. Epub 2019 Jul 22. Microb Drug Resist. 2019. PMID: 31329501
We thus collected 258 cloacal swabs from five different farms and selected ESC-R isolates to determine the current ESC-R prevalence and epidemiology. All five farms were ESC-R positive with proportions ranging from 4% to 67.3%. bla(CTX-M-1)/IncI1/ST3 was the …
We thus collected 258 cloacal swabs from five different farms and selected ESC-R isolates to determine the current ESC-R preva …
A Fully Integrated Miniaturized Optical Biosensor for Fast and Multiplexing Plasmonic Detection of High- and Low-Molecular-Weight Analytes.
Bolognesi M, Prosa M, Toerker M, Lopez Sanchez L, Wieczorek M, Giacomelli C, Benvenuti E, Pellacani P, Elferink A, Morschhauser A, Sola L, Damin F, Chiari M, Whatton M, Haenni E, Kallweit D, Marabelli F, Peters J, Toffanin S. Bolognesi M, et al. Adv Mater. 2023 Jun;35(26):e2208719. doi: 10.1002/adma.202208719. Epub 2023 May 5. Adv Mater. 2023. PMID: 36932736
Molecular characterization of highly prevalent Escherichia coli and Escherichia marmotae resistant to extended-spectrum cephalosporins in European starlings (Sturnus vulgaris) in Tunisia.
Souguir M, Châtre P, Drapeau A, François P, Azaiez S, Ncir S, Madec JY, Mansour W, Haenni M. Souguir M, et al. Microbiol Spectr. 2023 Sep 29;11(5):e0222023. doi: 10.1128/spectrum.02220-23. Online ahead of print. Microbiol Spectr. 2023. PMID: 37772831 Free PMC article.
The goal of our study was to estimate the proportion of ESC-R in these birds and to characterize the collected isolates using whole-genome sequencing. ...This species is phenotypically indistinguishable from Escherichia coli and has obviously the same capacity to acquire E …
The goal of our study was to estimate the proportion of ESC-R in these birds and to characterize the collected isolates using whole-g …
Multicentre evaluation of a selective isolation protocol for detection of mcr-positive E. coli and Salmonella spp. in food-producing animals and meat.
Perrin-Guyomard A, Granier SA, Slettemeås JS, Anjum M, Randall L, AbuOun M, Pauly N, Irrgang A, Hammerl JA, Kjeldgaard JS, Hammerum A, Franco A, Skarżyńska M, Kamińska E, Wasyl D, Dierikx C, Börjesson S, Geurts Y, Haenni M, Veldman K. Perrin-Guyomard A, et al. Lett Appl Microbiol. 2022 Aug;75(2):224-233. doi: 10.1111/lam.13717. Epub 2022 Apr 21. Lett Appl Microbiol. 2022. PMID: 35388505 Free PMC article.
Sensitivity of each agar medium to detect mcr-positive colistin-resistant E. coli or Salmonella spp. strains was 86% for CHROMID() Colistin R, 75% for CHROMagar(TM) COL-APSE and 70% for COLISTIGRAM. This combined method was effective to detect and isolate most of the E. co …
Sensitivity of each agar medium to detect mcr-positive colistin-resistant E. coli or Salmonella spp. strains was 86% for CHROMID() Colistin …
Temporal dynamics of the fecal microbiota in veal calves in a 6-month field trial.
Massot M, Haenni M, Nguyen TT, Madec JY, Mentré F, Denamur E. Massot M, et al. Anim Microbiome. 2020 Sep 15;2(1):32. doi: 10.1186/s42523-020-00052-6. Anim Microbiome. 2020. PMID: 33499974 Free PMC article.

There were moderate to strong positive associations between the dose of milk powder and the relative abundances of the genera Megasphaera, Enterococcus, Dialister and Mitsuokella, and the number of E. coli (r(s) 0.40; Bonferroni corrected p < 0.05). CONCLUSIONS: This ob

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There were moderate to strong positive associations between the dose of milk powder and the relative abundances of the genera Megasphaera, E …
Global transmission of extended-spectrum cephalosporin resistance in Escherichia coli driven by epidemic plasmids.
Zamudio R, Boerlin P, Mulvey MR, Haenni M, Beyrouthy R, Madec JY, Schwarz S, Cormier A, Chalmers G, Bonnet R, Zhanel GG, Kaspar H, Mather AE. Zamudio R, et al. EBioMedicine. 2024 Apr 11;103:105097. doi: 10.1016/j.ebiom.2024.105097. Online ahead of print. EBioMedicine. 2024. PMID: 38608515 Free PMC article.
To examine in detail the vehicles of transmission of the ESC-R genes, long- and short-read sequences were generated to obtain complete contiguous chromosome and plasmid sequences (n = 192 ESC-R E. coli). ...Finally, we found genetic signatures in the regions surroun …
To examine in detail the vehicles of transmission of the ESC-R genes, long- and short-read sequences were generated to obtain complet …
35 results