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Page 1
PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation.
Perike S, Gonzalez-Gonzalez FJ, Abu-Taha I, Damen FW, Hanft LM, Lizama KS, Aboonabi A, Capote AE, Aguilar-Sanchez Y, Levin B, Han Z, Sridhar A, Grand J, Martin J, Akar JG, Warren CM, Solaro RJ, Ong SG, Darbar D, McDonald KS, Goergen CJ, Wolska BM, Dobrev D, Wehrens XHT, McCauley MD. Perike S, et al. Circ Res. 2023 Oct 13;133(9):758-771. doi: 10.1161/CIRCRESAHA.123.322516. Epub 2023 Sep 22. Circ Res. 2023. PMID: 37737016
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity.
Landstrom AP, Yang Q, Sun B, Perelli RM, Bidzimou MT, Zhang Z, Aguilar-Sanchez Y, Alsina KM, Cao S, Reynolds JO, Word TA, van der Sangen NMR, Wells Q, Kannankeril PJ, Ludwig A, Kim JJ, Wehrens XHT. Landstrom AP, et al. Circ Arrhythm Electrophysiol. 2023 Feb;16(2):e010858. doi: 10.1161/CIRCEP.122.010858. Epub 2023 Jan 27. Circ Arrhythm Electrophysiol. 2023. PMID: 36706317 Free PMC article.
Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation.
Yin L, Zahradnikova A Jr, Rizzetto R, Boncompagni S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marqués-Sulé E, Aguilar-Sánchez Y, Fernández-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, Gerbaud P, Lai FA, Perrier R, Álvarez JL, Niggli E, Valdivia HH, Valdivia CR, Ramos-Franco J, Zorio E, Zissimopoulos S, Protasi F, Benitah JP, Gómez AM. Yin L, et al. Circ Res. 2021 Jul 23;129(3):e35-e52. doi: 10.1161/CIRCRESAHA.121.319094. Epub 2021 Jun 11. Circ Res. 2021. PMID: 34111951 Free PMC article.
Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation.
Tambeaux A, Aguilar-Sánchez Y, Santiago DJ, Mascitti M, DiNovo KM, Mejía-Alvarez R, Fill M, Wayne Chen SR, Ramos-Franco J. Tambeaux A, et al. Pflugers Arch. 2023 May;475(5):569-581. doi: 10.1007/s00424-023-02796-x. Epub 2023 Mar 7. Pflugers Arch. 2023. PMID: 36881190 Free PMC article.
Inositol 1,4,5-trisphosphate receptor (IP(3)R) and ryanodine receptor (RyR) are homologous cation channels that mediate release of Ca(2+) from the endoplasmic/sarcoplasmic reticulum (ER/SR) and thereby are involved in many physiological processes. In previous studies, we d …
Inositol 1,4,5-trisphosphate receptor (IP(3)R) and ryanodine receptor (RyR) are homologous cation channels that mediate release of Ca …
Topological versus spectral properties of random geometric graphs.
Aguilar-Sánchez R, Méndez-Bermúdez JA, Rodrigues FA, Sigarreta JM. Aguilar-Sánchez R, et al. Phys Rev E. 2020 Oct;102(4-1):042306. doi: 10.1103/PhysRevE.102.042306. Phys Rev E. 2020. PMID: 33212571
To evaluate the topological properties of RGGs we chose two well-known topological indices, the Randic index R(G) and the harmonic index H(G). We characterize the spectral and eigenvector properties of the corresponding randomly weighted adjacency matrices by the use of ra …
To evaluate the topological properties of RGGs we chose two well-known topological indices, the Randic index R(G) and the harmonic in …
Cross-cultural adaptation and validation of the STOP-bang Questionnaire from English to Spanish as a tool for the early detection of sleep apnea syndrome in the surgical patient and in the general population.
Mira Quirós MD, Maimó Bordoy A, El Haji K, Aguilar Sánchez JL, Tejada Gavela S. Mira Quirós MD, et al. Rev Esp Anestesiol Reanim (Engl Ed). 2022 Aug-Sep;69(7):393-401. doi: 10.1016/j.redare.2022.07.001. Epub 2022 Jul 20. Rev Esp Anestesiol Reanim (Engl Ed). 2022. PMID: 35871142
The reliability results were: a Cronbach's Alpha Coefficient of 0.767, a Pearson correlation r = 0.777 (P < .001) and a Sperman correlation rho = 0.455 (P = .044). ...

The reliability results were: a Cronbach's Alpha Coefficient of 0.767, a Pearson correlation r = 0.777 (P < .001) and a Sperman co

…
[Knowledge and attitudes of health professionals towards advance directives].
Aguilar-Sánchez JM, Cabañero-Martínez MJ, Puerta Fernández F, Ladios-Martín M, Fernández-de-Maya J, Cabrero-García J. Aguilar-Sánchez JM, et al. Gac Sanit. 2018 Jul-Aug;32(4):339-345. doi: 10.1016/j.gaceta.2017.08.006. Epub 2017 Oct 28. Gac Sanit. 2018. PMID: 29110888 Free article. Spanish.
Professionals had very positive attitudes towards the advance directives document (X=75.37;SD: 11.97;R=0-90), although their level of knowledge about them was medium-low (X=9.31;SD: 2.73;R=0-18). ...
Professionals had very positive attitudes towards the advance directives document (X=75.37;SD: 11.97;R=0-90), although their level of …
Ca2+ Sparks and Ca2+ waves are the subcellular events underlying Ca2+ overload during ischemia and reperfusion in perfused intact hearts.
Mattiazzi A, Argenziano M, Aguilar-Sanchez Y, Mazzocchi G, Escobar AL. Mattiazzi A, et al. J Mol Cell Cardiol. 2015 Feb;79:69-78. doi: 10.1016/j.yjmcc.2014.10.011. Epub 2014 Oct 28. J Mol Cell Cardiol. 2015. PMID: 25451173 Free PMC article.
However, little is known about the subcellular dynamics of Ca(2+) increase during I/R, and a possible role of the SR as a mechanism underlying this increase has been previously overlooked. ...We used confocal microscopy on mouse intact hearts loaded with Fluo-4. Hearts wer …
However, little is known about the subcellular dynamics of Ca(2+) increase during I/R, and a possible role of the SR as a mechanism u …