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Automated, calibration-free quantification of cortical bone porosity and geometry in postmenopausal osteoporosis from ultrashort echo time MRI and deep learning.
Jones BC, Wehrli FW, Kamona N, Deshpande RS, Vu BD, Song HK, Lee H, Grewal RK, Chan TJ, Witschey WR, MacLean MT, Josselyn NJ, Iyer SK, Al Mukaddam M, Snyder PJ, Rajapakse CS. Jones BC, et al. Bone. 2023 Jun;171:116743. doi: 10.1016/j.bone.2023.116743. Epub 2023 Mar 21. Bone. 2023. PMID: 36958542
RESULTS: The deep learning model provided accurate labeling (Dice score 0.93, intersection-over-union 0.88) and similar results to manual segmentation in quantifying cortical porosity (R(2) 0.97, ICC 0.98) and geometry (R(2) 0.82, ICC 0.75) parameters in vivo. ...Fi …
RESULTS: The deep learning model provided accurate labeling (Dice score 0.93, intersection-over-union 0.88) and similar results to manual se …
Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke.
Anderson CS, Robinson T, Lindley RI, Arima H, Lavados PM, Lee TH, Broderick JP, Chen X, Chen G, Sharma VK, Kim JS, Thang NH, Cao Y, Parsons MW, Levi C, Huang Y, Olavarría VV, Demchuk AM, Bath PM, Donnan GA, Martins S, Pontes-Neto OM, Silva F, Ricci S, Roffe C, Pandian J, Billot L, Woodward M, Li Q, Wang X, Wang J, Chalmers J; ENCHANTED Investigators and Coordinators. Anderson CS, et al. N Engl J Med. 2016 Jun 16;374(24):2313-23. doi: 10.1056/NEJMoa1515510. Epub 2016 May 10. N Engl J Med. 2016. PMID: 27161018 Free article. Clinical Trial.
A multi-imaging modality study of bone density, bone structure and the muscle - bone unit in end-stage renal disease.
Leonard MB, Wehrli FW, Ziolkowski SL, Billig E, Long J, Nickolas TL, Magland JF, Nihtianova S, Zemel BS, Herskovitz R, Rajapakse CS. Leonard MB, et al. Bone. 2019 Oct;127:271-279. doi: 10.1016/j.bone.2019.05.022. Epub 2019 May 31. Bone. 2019. PMID: 31158505
ALMI was positively associated with total hip, femoral neck, ultradistal radius and 1/3rd radius aBMD and with tibia cortical thickness (R = 0.46 to 0.64). Adjustment for ALMI significantly attenuated bone deficits at these sites: e.g. mean femoral neck aBMD was 0.7 …
ALMI was positively associated with total hip, femoral neck, ultradistal radius and 1/3rd radius aBMD and with tibia cortical thickness ( …
Effects of testosterone and growth hormone on the structural and mechanical properties of bone by micro-MRI in the distal tibia of men with hypopituitarism.
Al Mukaddam M, Rajapakse CS, Bhagat YA, Wehrli FW, Guo W, Peachey H, LeBeau SO, Zemel BS, Wang C, Swerdloff RS, Kapoor SC, Snyder PJ. Al Mukaddam M, et al. J Clin Endocrinol Metab. 2014 Apr;99(4):1236-44. doi: 10.1210/jc.2013-3665. Epub 2014 Jan 13. J Clin Endocrinol Metab. 2014. PMID: 24423356 Free PMC article. Clinical Trial.
Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis.
Ming XF, Rajapakse AG, Yepuri G, Xiong Y, Carvas JM, Ruffieux J, Scerri I, Wu Z, Popp K, Li J, Sartori C, Scherrer U, Kwak BR, Montani JP, Yang Z. Ming XF, et al. J Am Heart Assoc. 2012 Aug;1(4):e000992. doi: 10.1161/JAHA.112.000992. Epub 2012 Aug 24. J Am Heart Assoc. 2012. PMID: 23130157 Free PMC article.
Finite element analysis applied to 3-T MR imaging of proximal femur microarchitecture: lower bone strength in patients with fragility fractures compared with control subjects.
Chang G, Honig S, Brown R, Deniz CM, Egol KA, Babb JS, Regatte RR, Rajapakse CS. Chang G, et al. Radiology. 2014 Aug;272(2):464-74. doi: 10.1148/radiol.14131926. Epub 2014 Apr 2. Radiology. 2014. PMID: 24689884 Free PMC article.
The Mann-Whitney test was used to compare bone mineral density T scores and elastic moduli between the groups. The relationship (R(2)) between elastic moduli and bone mineral density T scores was assessed. ...There were weak relationships between elastic moduli and bone mi …
The Mann-Whitney test was used to compare bone mineral density T scores and elastic moduli between the groups. The relationship (R(2) …
11 results