Severe vancomycin-induced anaphylactic reaction

Medicina (Kaunas). 2010;46(1):30-3.

Abstract

Vancomycin is widely used against methicillin-resistant Staphylococcus aureus infections, but it is associated with many adverse effects such as nephrotoxicity, ototoxicity, gastrointestinal disturbances, blood disorders, and two types of hypersensitivity reactions - an anaphylactoid reaction known as "red man syndrome" and anaphylaxis. We report a case of a 23-year-old man who developed a vancomycin-induced anaphylactic reaction in the treatment of methicillin-resistant Staphylococcus aureus infection.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Administration, Oral
  • Adult
  • Anaphylaxis / chemically induced*
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Female
  • Humans
  • Infant
  • Male
  • Methicillin Resistance
  • Methicillin-Resistant Staphylococcus aureus*
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / therapeutic use*
  • Middle Aged
  • Prednisolone / administration & dosage
  • Prednisolone / therapeutic use*
  • Staphylococcal Infections / drug therapy*
  • Time Factors
  • Treatment Outcome
  • Vancomycin / administration & dosage
  • Vancomycin / adverse effects*
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Vancomycin
  • Prednisolone
  • Methylprednisolone