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Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores.
Smurova K, Damizia M, Irene C, Stancari S, Berto G, Perticari G, Iacovella MG, D'Ambrosio I, Giubettini M, Philippe R, Baggio C, Callegaro E, Casagranda A, Corsini A, Polese VG, Ricci A, Dassi E, De Wulf P. Smurova K, et al. Among authors: philippe r. Nat Commun. 2023 Jun 1;14(1):3172. doi: 10.1038/s41467-023-38920-9. Nat Commun. 2023. PMID: 37263996 Free PMC article.
The p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis.
Burgos M, Philippe R, Antigny F, Buscaglia P, Masson E, Mukherjee S, Dubar P, Le Maréchal C, Campeotto F, Lebonvallet N, Frieden M, Llopis J, Domingo B, Stathopulos PB, Ikura M, Brooks W, Guida W, Chen JM, Ferec C, Capiod T, Mignen O. Burgos M, et al. Among authors: philippe r. J Cell Sci. 2021 Feb 10;134(3):jcs244012. doi: 10.1242/jcs.244012. J Cell Sci. 2021. PMID: 33468626
GCN5 contributes to intracellular lipid accumulation in human primary cardiac stromal cells from patients affected by Arrhythmogenic cardiomyopathy.
Volani C, Pagliaro A, Rainer J, Paglia G, Porro B, Stadiotti I, Foco L, Cogliati E, Paolin A, Lagrasta C, Frati C, Corradini E, Falco A, Matzinger T, Picard A, Ermon B, Piazza S, De Bortoli M, Tondo C, Philippe R, Medici A, Lavdas AA, Blumer MJF, Pompilio G, Sommariva E, Pramstaller PP, Troppmair J, Meraviglia V, Rossini A. Volani C, et al. Among authors: philippe r. J Cell Mol Med. 2022 Jul;26(13):3687-3701. doi: 10.1111/jcmm.17396. Epub 2022 Jun 16. J Cell Mol Med. 2022. PMID: 35712781 Free PMC article.
PAR2, Keratinocytes, and Cathepsin S Mediate the Sensory Effects of Ciguatoxins Responsible for Ciguatera Poisoning.
L'Herondelle K, Pierre O, Fouyet S, Leschiera R, Le Gall-Ianotto C, Philippe R, Buscaglia P, Mignen O, Talagas M, Lewis RJ, Michel L, Misery L, Le Garrec R. L'Herondelle K, et al. Among authors: philippe r. J Invest Dermatol. 2021 Mar;141(3):648-658.e3. doi: 10.1016/j.jid.2020.07.020. Epub 2020 Aug 13. J Invest Dermatol. 2021. PMID: 32800876 Free article.
Major Role for TRPV1 and InsP3R in PAR2-Elicited Inflammatory Mediator Production in Differentiated Human Keratinocytes.
Gouin O, L'Herondelle K, Buscaglia P, Le Gall-Ianotto C, Philippe R, Legoux N, Mignen O, Buhé V, Leschiera R, Sakka M, Kerfant N, Carré JL, Le Garrec R, Lefeuvre L, Lebonvallet N, Misery L. Gouin O, et al. Among authors: philippe r. J Invest Dermatol. 2018 Jul;138(7):1564-1572. doi: 10.1016/j.jid.2018.01.034. Epub 2018 Feb 17. J Invest Dermatol. 2018. PMID: 29458120 Free article.