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Year Number of Results
1995 2
1997 1
1998 2
1999 2
2000 3
2001 2
2003 4
2004 8
2005 7
2006 8
2007 15
2008 15
2009 14
2010 12
2011 13
2012 29
2013 35
2014 42
2015 40
2016 26
2017 26
2018 27
2019 28
2020 36
2021 40
2022 37
2023 40
2024 14

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480 results

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Page 1
Update on gut microbiota in cardiovascular diseases.
Qian B, Zhang K, Li Y, Sun K. Qian B, et al. Front Cell Infect Microbiol. 2022 Nov 10;12:1059349. doi: 10.3389/fcimb.2022.1059349. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36439214 Free PMC article. Review.
It has also been revealed that intestinal flora-related metabolites, such as trimethylamine-N-oxide (TMAO), short-chain fatty acids (SCFA) and bile acids (BAs), are also related to the development, prevention, treatment and prognosis of CVDs. ...
It has also been revealed that intestinal flora-related metabolites, such as trimethylamine-N-oxide (TMAO), short-chain fatty acids ( …
The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease.
Zhu H, Cao C, Wu Z, Zhang H, Sun Z, Wang M, Xu H, Zhao Z, Wang Y, Pei G, Yang Q, Zhu F, Yang J, Deng X, Hong Y, Li Y, Sun J, Zhu F, Shi M, Qian K, Ye T, Zuo X, Zhao F, Guo J, Xu G, Yao Y, Zeng R. Zhu H, et al. Cell Metab. 2021 Oct 5;33(10):1926-1942.e8. doi: 10.1016/j.cmet.2021.06.014. Epub 2021 Jul 15. Cell Metab. 2021. PMID: 34270930 Free article.
Here, we show that oral administration of the probiotic Lactobacillus casei Zhang (L. casei Zhang) corrected bilateral renal ischemia-reperfusion (I/R)-induced gut microbial dysbiosis, alleviated kidney injury, and delayed its progression to CKD in mice. L. casei Zhang elevated t …
Here, we show that oral administration of the probiotic Lactobacillus casei Zhang (L. casei Zhang) corrected bilateral renal ischemia-reperf …
Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage.
Zhang Y, Fang Q, Wang H, Qi J, Sun S, Liao M, Wu Y, Hu Y, Jiang P, Cheng C, Qian X, Tang M, Cao W, Xiang S, Zhang C, Yang J, Gao X, Ying Z, Chai R. Zhang Y, et al. Autophagy. 2023 Jan;19(1):75-91. doi: 10.1080/15548627.2022.2062872. Epub 2022 Apr 26. Autophagy. 2023. PMID: 35471096 Free PMC article.
Importantly, treatment with a mitophagy activator could rescue neomycin-treated hair cells by increasing mitophagy, indicating that genetic modulation or drug intervention in mitophagy may have therapeutic potential for aminoglycoside-induced hearing loss.Abbreviations: AAV: aden …
Importantly, treatment with a mitophagy activator could rescue neomycin-treated hair cells by increasing mitophagy, indicating that genetic …
ACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathway.
Zhang Q, Lu S, Li T, Yu L, Zhang Y, Zeng H, Qian X, Bi J, Lin Y. Zhang Q, et al. J Exp Clin Cancer Res. 2019 Apr 25;38(1):173. doi: 10.1186/s13046-019-1156-5. J Exp Clin Cancer Res. 2019. PMID: 31023337 Free PMC article.
ACE2 expression in breast cancer tissue was estimated by reverse transcription-quantitative polymerase chain reaction (qPCR). Breast cancer cell migration, proliferation and angiogenesis were assessed by Transwell migration, proliferation, tube formation, and wound healing …
ACE2 expression in breast cancer tissue was estimated by reverse transcription-quantitative polymerase chain reaction (qPCR). Breast …
Fecal Signatures of Streptococcus anginosus and Streptococcus constellatus for Noninvasive Screening and Early Warning of Gastric Cancer.
Zhou CB, Pan SY, Jin P, Deng JW, Xue JH, Ma XY, Xie YH, Cao H, Liu Q, Xie WF, Zou XP, Sheng JQ, Wang BM, Wang H, Ren JL, Liu SD, Sun YW, Meng XJ, Zhao G, Chen JX, Cui Y, Wang PQ, Guo HM, Yang L, Chen X, Ding J, Yang XN, Wang XK, Qian AH, Hou LD, Wang Z, Chen YX, Fang JY. Zhou CB, et al. Gastroenterology. 2022 Jun;162(7):1933-1947.e18. doi: 10.1053/j.gastro.2022.02.015. Epub 2022 Feb 12. Gastroenterology. 2022. PMID: 35167866
Their relative abundances were detected using quantitative real-time polymerase chain reaction to test them as bacterial candidates in the training cohort. ...
Their relative abundances were detected using quantitative real-time polymerase chain reaction to test them as bacterial candidates i …
Human umbilical cord mesenchymal stem cells ameliorate colon inflammation via modulation of gut microbiota-SCFAs-immune axis.
Liu A, Liang X, Wang W, Wang C, Song J, Guo J, Sun D, Wang D, Song M, Qian J, Zhang X. Liu A, et al. Stem Cell Res Ther. 2023 Sep 25;14(1):271. doi: 10.1186/s13287-023-03471-9. Stem Cell Res Ther. 2023. PMID: 37749611 Free PMC article.
METHODS: Here, we investigated for the first time the role of gut microbiota in mediating the protective effect of human umbilical cord MSCs (HUMSCs) on DSS-induced colitis. Gut microbiota alteration and short-chain fatty acids (SCFAs) production were analyzed through 16S …
METHODS: Here, we investigated for the first time the role of gut microbiota in mediating the protective effect of human umbilical cord MSCs …
Aptamer-based biosensors and application in tumor theranostics.
Mo T, Liu X, Luo Y, Zhong L, Zhang Z, Li T, Gan L, Liu X, Li L, Wang H, Sun X, Fan D, Qian Z, Wu P, Chen X. Mo T, et al. Cancer Sci. 2022 Jan;113(1):7-16. doi: 10.1111/cas.15194. Epub 2021 Nov 16. Cancer Sci. 2022. PMID: 34747552 Free PMC article. Review.
An aptamer is a short oligonucleotide chain that can specifically recognize targeting analytes. Due to its high specificity, low cost, and good biocompatibility, aptamers as the targeting elements of biosensors have been applied widely in non-invasive tumor imaging and tre …
An aptamer is a short oligonucleotide chain that can specifically recognize targeting analytes. Due to its high specificity, low cost …
Serglycin in human cancers.
Li XJ, Qian CN. Li XJ, et al. Chin J Cancer. 2011 Sep;30(9):585-9. doi: 10.5732/cjc.011.10314. Chin J Cancer. 2011. PMID: 21880179 Free PMC article. Review.
Serglycin belongs to a family of small proteoglycans with Ser-Gly dipeptide repeats, and it is modified with different types of glycosaminoglycan side chains. Intracellular serglycin affects the retention and secretion of proteases, chemokines, or other cytokines by physic …
Serglycin belongs to a family of small proteoglycans with Ser-Gly dipeptide repeats, and it is modified with different types of glycosaminog …
Structural basis for catalysis and substrate specificity of human ACAT1.
Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, Du X, Yang H, Wong CCL, Yan N. Qian H, et al. Nature. 2020 May;581(7808):333-338. doi: 10.1038/s41586-020-2290-0. Epub 2020 May 13. Nature. 2020. PMID: 32433614
This structural and biochemical characterization helps to rationalize the preference of ACAT1 for unsaturated acyl chains, and provides insight into the catalytic mechanism of enzymes within the MBOAT family(8)....
This structural and biochemical characterization helps to rationalize the preference of ACAT1 for unsaturated acyl chains, and provid …
0.9% saline is neither normal nor physiological.
Li H, Sun SR, Yap JQ, Chen JH, Qian Q. Li H, et al. J Zhejiang Univ Sci B. 2016 Mar;17(3):181-7. doi: 10.1631/jzus.B1500201. J Zhejiang Univ Sci B. 2016. PMID: 26984838 Free PMC article. Review.
Saline overload (80 ml/kg) in rodents can cause intestinal edema and contractile dysfunction associated with activation of sodium-proton exchanger (NHE) and decrease in myosin light chain phosphorylation. Saline infusion can also adversely affect renal hemodynamics. ...
Saline overload (80 ml/kg) in rodents can cause intestinal edema and contractile dysfunction associated with activation of sodium-proton exc …
480 results