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Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy.
Mukhopadhyay S, Huang HY, Lin Z, Ranieri M, Li S, Sahu S, Liu Y, Ban Y, Guidry K, Hu H, Lopez A, Sherman F, Tan YJ, Lee YT, Armstrong AP, Dolgalev I, Sahu P, Zhang T, Lu W, Gray NS, Christensen JG, Tang TT, Velcheti V, Khodadadi-Jamayran A, Wong KK, Neel BG. Mukhopadhyay S, et al. Among authors: sahu p. Cancer Res. 2023 Dec 15;83(24):4095-4111. doi: 10.1158/0008-5472.CAN-23-2729. Cancer Res. 2023. PMID: 37729426
Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
Tong X, Patel AS, Kim E, Li H, Chen Y, Li S, Liu S, Dilly J, Kapner KS, Zhang N, Xue Y, Hover L, Mukhopadhyay S, Sherman F, Myndzar K, Sahu P, Gao Y, Li F, Li F, Fang Z, Jin Y, Gao J, Shi M, Sinha S, Chen L, Chen Y, Kheoh T, Yang W, Yanai I, Moreira AL, Velcheti V, Neel BG, Hu L, Christensen JG, Olson P, Gao D, Zhang MQ, Aguirre AJ, Wong KK, Ji H. Tong X, et al. Among authors: sahu p. Cancer Cell. 2024 Mar 11;42(3):413-428.e7. doi: 10.1016/j.ccell.2024.01.012. Epub 2024 Feb 22. Cancer Cell. 2024. PMID: 38402609 Free article.
Recent advances in experimental animal models of lung cancer.
Malyla V, Paudel KR, Shukla SD, Donovan C, Wadhwa R, Pickles S, Chimankar V, Sahu P, Bielefeldt-Ohmann H, Bebawy M, Hansbro PM, Dua K. Malyla V, et al. Among authors: sahu p. Future Med Chem. 2020 Apr;12(7):567-570. doi: 10.4155/fmc-2019-0338. Epub 2020 Mar 16. Future Med Chem. 2020. PMID: 32175774 Review. No abstract available.
Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion.
Donovan C, Kim RY, Galvao I, Jarnicki AG, Brown AC, Jones-Freeman B, Gomez HM, Wadhwa R, Hortle E, Jayaraman R, Khan H, Pickles S, Sahu P, Chimankar V, Tu X, Ali MK, Mayall JR, Nguyen DH, Budden KF, Kumar V, Schroder K, Robertson AA, Cooper MA, Wark PA, Oliver BG, Horvat JC, Hansbro PM. Donovan C, et al. Among authors: sahu p. Immunol Cell Biol. 2022 Apr;100(4):235-249. doi: 10.1111/imcb.12537. Epub 2022 Mar 21. Immunol Cell Biol. 2022. PMID: 35175629 Free PMC article.