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Activated brown adipose tissue releases exosomes containing mitochondrial methylene tetrahydrofolate dehydrogenase (NADP dependent) 1-like protein (MTHFD1L).
Leow MK, Rengaraj A, Narasimhan K, Verma SK, Yaligar J, Thu GLT, Sun L, Goh HJ, Govindharajulu P, Sadananthan SA, Michael N, Meng W, Gallart-Palau X, Sun L, Karnani N, Sze NSK, Velan SS. Leow MK, et al. Among authors: govindharajulu p. Biosci Rep. 2022 May 27;42(5):BSR20212543. doi: 10.1042/BSR20212543. Biosci Rep. 2022. PMID: 35502767 Free PMC article.
Metabolic effects of brown fat in transitioning from hyperthyroidism to euthyroidism.
Sun L, Goh HJ, Verma S, Govindharajulu P, Sadananthan SA, Michael N, Jadegoud Y, Henry CJ, Velan SS, Yeo PS, Lee Y, Lim BSP, Liew H, Chew CK, Quek TPL, Abdul Shakoor SAKK, Hoi WH, Chan SP, Chew DE, Dalan R, Leow MKS. Sun L, et al. Among authors: govindharajulu p. Eur J Endocrinol. 2021 Aug 27;185(4):553-563. doi: 10.1530/EJE-21-0366. Eur J Endocrinol. 2021. PMID: 34342595 Free PMC article. Clinical Trial.
Brown Adipose Tissue: Multimodality Evaluation by PET, MRI, Infrared Thermography, and Whole-Body Calorimetry (TACTICAL-II).
Sun L, Verma S, Michael N, Chan SP, Yan J, Sadananthan SA, Camps SG, Goh HJ, Govindharajulu P, Totman J, Townsend D, Goh JP, Sun L, Boehm BO, Lim SC, Sze SK, Henry CJ, Hu HH, Velan SS, Leow MK. Sun L, et al. Among authors: govindharajulu p. Obesity (Silver Spring). 2019 Sep;27(9):1434-1442. doi: 10.1002/oby.22560. Epub 2019 Jul 13. Obesity (Silver Spring). 2019. PMID: 31301122 Free PMC article.
Capsinoids activate brown adipose tissue (BAT) with increased energy expenditure associated with subthreshold 18-fluorine fluorodeoxyglucose uptake in BAT-positive humans confirmed by positron emission tomography scan.
Sun L, Camps SG, Goh HJ, Govindharajulu P, Schaefferkoetter JD, Townsend DW, Verma SK, Velan SS, Sun L, Sze SK, Lim SC, Boehm BO, Henry CJ, Leow MK. Sun L, et al. Among authors: govindharajulu p. Am J Clin Nutr. 2018 Jan 1;107(1):62-70. doi: 10.1093/ajcn/nqx025. Am J Clin Nutr. 2018. PMID: 29381803 Free article.