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The Paradox of Coenzyme Q10 in Aging.
Díaz-Casado ME, Quiles JL, Barriocanal-Casado E, González-García P, Battino M, López LC, Varela-López A. Díaz-Casado ME, et al. Among authors: gonzalez garcia p. Nutrients. 2019 Sep 14;11(9):2221. doi: 10.3390/nu11092221. Nutrients. 2019. PMID: 31540029 Free PMC article. Review.
Metabolic Targets of Coenzyme Q10 in Mitochondria.
Hidalgo-Gutiérrez A, González-García P, Díaz-Casado ME, Barriocanal-Casado E, López-Herrador S, Quinzii CM, López LC. Hidalgo-Gutiérrez A, et al. Among authors: gonzalez garcia p. Antioxidants (Basel). 2021 Mar 26;10(4):520. doi: 10.3390/antiox10040520. Antioxidants (Basel). 2021. PMID: 33810539 Free PMC article. Review.
The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency.
González-García P, Díaz-Casado ME, Hidalgo-Gutiérrez A, Jiménez-Sánchez L, Bakkali M, Barriocanal-Casado E, Escames G, Chiozzi RZ, Völlmy F, Zaal EA, Berkers CR, Heck AJR, López LC. González-García P, et al. Redox Biol. 2022 Sep;55:102403. doi: 10.1016/j.redox.2022.102403. Epub 2022 Jul 15. Redox Biol. 2022. PMID: 35863266 Free PMC article.
Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress.
Martinez-Ruiz L, Florido J, Rodriguez-Santana C, López-Rodríguez A, Guerra-Librero A, Fernández-Gil BI, García-Tárraga P, Garcia-Verdugo JM, Oppel F, Sudhoff H, Sánchez-Porras D, Ten-Steve A, Fernández-Martínez J, González-García P, Rusanova I, Acuña-Castroviejo D, Carriel V, Escames G. Martinez-Ruiz L, et al. Among authors: gonzalez garcia p. Biomed Pharmacother. 2023 Nov;167:115518. doi: 10.1016/j.biopha.2023.115518. Epub 2023 Sep 15. Biomed Pharmacother. 2023. PMID: 37717534 Free article.
β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight.
Hidalgo-Gutiérrez A, Barriocanal-Casado E, Díaz-Casado ME, González-García P, Zenezini Chiozzi R, Acuña-Castroviejo D, López LC. Hidalgo-Gutiérrez A, et al. Among authors: gonzalez garcia p. Biomedicines. 2021 Oct 13;9(10):1457. doi: 10.3390/biomedicines9101457. Biomedicines. 2021. PMID: 34680574 Free PMC article.
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.
González-García P, Hidalgo-Gutiérrez A, Mascaraque C, Barriocanal-Casado E, Bakkali M, Ziosi M, Abdihankyzy UB, Sánchez-Hernández S, Escames G, Prokisch H, Martín F, Quinzii CM, López LC. González-García P, et al. Hum Mol Genet. 2020 Nov 25;29(19):3296-3311. doi: 10.1093/hmg/ddaa214. Hum Mol Genet. 2020. PMID: 32975579 Free PMC article.