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Page 1
Selective Inhibitors of Human Neuraminidase 3.
Guo T, Dätwyler P, Demina E, Richards MR, Ge P, Zou C, Zheng R, Fougerat A, Pshezhetsky AV, Ernst B, Cairo CW. Guo T, et al. Among authors: datwyler p. J Med Chem. 2018 Mar 8;61(5):1990-2008. doi: 10.1021/acs.jmedchem.7b01574. Epub 2018 Feb 21. J Med Chem. 2018. PMID: 29425031
Improvement of Aglycone π-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists.
Schönemann W, Cramer J, Mühlethaler T, Fiege B, Silbermann M, Rabbani S, Dätwyler P, Zihlmann P, Jakob RP, Sager CP, Smieško M, Schwardt O, Maier T, Ernst B. Schönemann W, et al. Among authors: datwyler p. ChemMedChem. 2019 Apr 3;14(7):749-757. doi: 10.1002/cmdc.201900051. Epub 2019 Feb 22. ChemMedChem. 2019. PMID: 30710416
Activities of N,N'-Diarylurea MMV665852 analogs against Schistosoma mansoni.
Cowan N, Dätwyler P, Ernst B, Wang C, Vennerstrom JL, Spangenberg T, Keiser J. Cowan N, et al. Among authors: datwyler p. Antimicrob Agents Chemother. 2015 Apr;59(4):1935-41. doi: 10.1128/AAC.04463-14. Epub 2015 Jan 12. Antimicrob Agents Chemother. 2015. PMID: 25583726 Free PMC article.
Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease.
de Matos AM, Blázquez-Sánchez MT, Bento-Oliveira A, de Almeida RFM, Nunes R, Lopes PEM, Machuqueiro M, Cristóvão JS, Gomes CM, Souza CS, El Idrissi IG, Colabufo NA, Diniz A, Marcelo F, Oliveira MC, López Ó, Fernandez-Bolaños JG, Dätwyler P, Ernst B, Ning K, Garwood C, Chen B, Rauter AP. de Matos AM, et al. Among authors: datwyler p. J Med Chem. 2020 Oct 22;63(20):11663-11690. doi: 10.1021/acs.jmedchem.0c00841. Epub 2020 Oct 13. J Med Chem. 2020. PMID: 32959649 Free article.
Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells.
de Matos AM, Martins A, Man T, Evans D, Walter M, Oliveira MC, López Ó, Fernandez-Bolaños JG, Dätwyler P, Ernst B, Macedo MP, Contino M, Colabufo NA, Rauter AP. de Matos AM, et al. Among authors: datwyler p. Pharmaceuticals (Basel). 2019 Jun 21;12(2):98. doi: 10.3390/ph12020098. Pharmaceuticals (Basel). 2019. PMID: 31234364 Free PMC article.