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Page 1
Concepts and Core Principles of Fragment-Based Drug Design.
Molecules. 2019 Nov 26;24(23):4309. doi: 10.3390/molecules24234309.
Molecules. 2019.
PMID: 31779114
Free PMC article.
Review.
Towards Zwitterionic Oligonucleotides with Improved Properties: the NAA/LNA-Gapmer Approach.
Wojtyniak M, Schmidtgall B, Kirsch P, Ducho C.
Wojtyniak M, et al. Among authors: kirsch p.
Chembiochem. 2020 Nov 16;21(22):3234-3243. doi: 10.1002/cbic.202000450. Epub 2020 Aug 28.
Chembiochem. 2020.
PMID: 32662164
Free PMC article.
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Discovery of Novel Latency-Associated Nuclear Antigen Inhibitors as Antiviral Agents Against Kaposi's Sarcoma-Associated Herpesvirus.
Kirsch P, Jakob V, Elgaher WAM, Walt C, Oberhausen K, Schulz TF, Empting M.
Kirsch P, et al.
ACS Chem Biol. 2020 Feb 21;15(2):388-395. doi: 10.1021/acschembio.9b00845. Epub 2020 Jan 24.
ACS Chem Biol. 2020.
PMID: 31944659
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Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi's sarcoma-associated herpesvirus infections.
Kirsch P, Stein SC, Berwanger A, Rinkes J, Jakob V, Schulz TF, Empting M.
Kirsch P, et al.
Eur J Med Chem. 2020 Sep 15;202:112525. doi: 10.1016/j.ejmech.2020.112525. Epub 2020 Jun 28.
Eur J Med Chem. 2020.
PMID: 32634628
Free article.
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Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8.
Kirsch P, Jakob V, Oberhausen K, Stein SC, Cucarro I, Schulz TF, Empting M.
Kirsch P, et al.
J Med Chem. 2019 Apr 25;62(8):3924-3939. doi: 10.1021/acs.jmedchem.8b01827. Epub 2019 Apr 12.
J Med Chem. 2019.
PMID: 30888817
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A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56.
Schifrin A, Khatri Y, Kirsch P, Thiel V, Schulz S, Bernhardt R.
Schifrin A, et al. Among authors: kirsch p.
Org Biomol Chem. 2016 Apr 7;14(13):3385-93. doi: 10.1039/c6ob00130k. Epub 2016 Mar 7.
Org Biomol Chem. 2016.
PMID: 26947062
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