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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1977 1
1983 1
1985 1
1987 1
1990 2
1996 2
1997 3
1998 10
1999 11
2000 17
2001 33
2002 30
2003 35
2004 27
2005 38
2006 44
2007 46
2008 53
2009 57
2010 58
2011 65
2012 69
2013 62
2014 80
2015 110
2016 107
2017 119
2018 95
2019 152
2020 140
2021 108
2022 114
2023 103
2024 45

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1,612 results

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The following term was not found in PubMed: Saa-Perez
Page 1
Emergency Contraception.
Batur P, Kransdorf LN, Casey PM. Batur P, et al. Mayo Clin Proc. 2016 Jun;91(6):802-7. doi: 10.1016/j.mayocp.2016.02.018. Mayo Clin Proc. 2016. PMID: 27261868 Free article. Review.
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Han Y, et al. Nature. 2021 Jan;589(7841):270-275. doi: 10.1038/s41586-020-2901-9. Epub 2020 Oct 28. Nature. 2021. PMID: 33116299 Free PMC article.
Using hPSC-LOs, we performed a high-throughput screen of drugs approved by the FDA (US Food and Drug Administration) and identified entry inhibitors of SARS-CoV-2, including imatinib, mycophenolic acid and quinacrine dihydrochloride. ...Together, these data demonstrate tha …
Using hPSC-LOs, we performed a high-throughput screen of drugs approved by the FDA (US Food and Drug Administration) and identified e …
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD. Lasko LM, et al. Nature. 2017 Oct 5;550(7674):128-132. doi: 10.1038/nature24028. Epub 2017 Sep 27. Nature. 2017. PMID: 28953875 Free PMC article.
Histone deacetylase inhibitors are currently approved to treat certain cancers, but progress on the development of drug-like histone actyltransferase inhibitors has lagged behind. ...Current inhibitors of the p300 and CBP histone acetyltransferase domains, including natura …
Histone deacetylase inhibitors are currently approved to treat certain cancers, but progress on the development of drug-like histone …
An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence.
Dhimolea E, de Matos Simoes R, Kansara D, Al'Khafaji A, Bouyssou J, Weng X, Sharma S, Raja J, Awate P, Shirasaki R, Tang H, Glassner BJ, Liu Z, Gao D, Bryan J, Bender S, Roth J, Scheffer M, Jeselsohn R, Gray NS, Georgakoudi I, Vazquez F, Tsherniak A, Chen Y, Welm A, Duy C, Melnick A, Bartholdy B, Brown M, Culhane AC, Mitsiades CS. Dhimolea E, et al. Cancer Cell. 2021 Feb 8;39(2):240-256.e11. doi: 10.1016/j.ccell.2020.12.002. Epub 2021 Jan 7. Cancer Cell. 2021. PMID: 33417832 Free PMC article.
In cancer cells, depleting Myc or inhibiting Brd4, a Myc transcriptional co-activator, attenuates drug cytotoxicity through a dormant diapause-like adaptation with reduced apoptotic priming. ...
In cancer cells, depleting Myc or inhibiting Brd4, a Myc transcriptional co-activator, attenuates drug cytotoxicity through a dormant …
Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6.
Jiang B, Wang ES, Donovan KA, Liang Y, Fischer ES, Zhang T, Gray NS. Jiang B, et al. Angew Chem Int Ed Engl. 2019 May 6;58(19):6321-6326. doi: 10.1002/anie.201901336. Epub 2019 Mar 29. Angew Chem Int Ed Engl. 2019. PMID: 30802347 Free PMC article.
We found that in mantle cell lymphoma cell lines, combined IKZF1/3 degradation with dual CDK4/6 degradation produced enhanced anti-proliferative effects compared to CDK4/6 inhibition, CDK4/6 degradation, or IKZF1/3 degradation. ...
We found that in mantle cell lymphoma cell lines, combined IKZF1/3 degradation with dual CDK4/6 degradation produced enhanced anti-prolifera …
α-Ketoglutarate links p53 to cell fate during tumour suppression.
Morris JP 4th, Yashinskie JJ, Koche R, Chandwani R, Tian S, Chen CC, Baslan T, Marinkovic ZS, Sánchez-Rivera FJ, Leach SD, Carmona-Fontaine C, Thompson CB, Finley LWS, Lowe SW. Morris JP 4th, et al. Nature. 2019 Sep;573(7775):595-599. doi: 10.1038/s41586-019-1577-5. Epub 2019 Sep 18. Nature. 2019. PMID: 31534224 Free PMC article.
Increased levels of the alphaKG-dependent chromatin modification 5-hydroxymethylcytosine (5hmC) accompany the tumour-cell differentiation that is triggered by p53, whereas decreased 5hmC characterizes the transition from premalignant to de-differentiated malignant lesions …
Increased levels of the alphaKG-dependent chromatin modification 5-hydroxymethylcytosine (5hmC) accompany the tumour-cell differentiation th …
Blindsight.
Stoerig P, Cowey A. Stoerig P, et al. Curr Biol. 2007 Oct 9;17(19):R822-4. doi: 10.1016/j.cub.2007.07.016. Curr Biol. 2007. PMID: 17925204 Free article. Review. No abstract available.
The effect of antibiotics on the composition of the intestinal microbiota - a systematic review.
Zimmermann P, Curtis N. Zimmermann P, et al. J Infect. 2019 Dec;79(6):471-489. doi: 10.1016/j.jinf.2019.10.008. Epub 2019 Oct 18. J Infect. 2019. PMID: 31629863
CONCLUSION: Antibiotics have profound and sometimes persisting effects on the intestinal microbiota, characterised by diminished abundance of beneficial commensals and increased abundance of potentially detrimental microorganisms. Understanding these effects will he …
CONCLUSION: Antibiotics have profound and sometimes persisting effects on the intestinal microbiota, characterised by diminished abun …
[Topical antiseptic agents].
Staubach P, Melhorn S. Staubach P, et al. Hautarzt. 2017 Oct;68(10):835-851. doi: 10.1007/s00105-017-4033-1. Hautarzt. 2017. PMID: 28887578 Review. German.
Antimicrobial Effects of Antipyretics.
Zimmermann P, Curtis N. Zimmermann P, et al. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02268-16. doi: 10.1128/AAC.02268-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28137805 Free PMC article. Review.
Since they are often coadministered with antimicrobial therapy, it is important to understand the interactions between these two classes of drugs. Our review is the first to summarize the antimicrobial effects of antipyretic drugs and the underlying mechanisms involved. .. …
Since they are often coadministered with antimicrobial therapy, it is important to understand the interactions between these two classes of …
1,612 results