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Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8+ T cells.
Riegel D, Romero-Fernández E, Simon M, Adenugba AR, Singer K, Mayr R, Weber F, Kleemann M, Imbusch CD, Kreutz M, Brors B, Ugele I, Werner JM, Siska PJ, Schmidl C. Riegel D, et al. Among authors: siska pj. Mol Cell. 2023 Feb 16;83(4):622-636.e10. doi: 10.1016/j.molcel.2022.12.029. Epub 2023 Jan 18. Mol Cell. 2023. PMID: 36657444 Free article.
The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality.
Li C, Zhu B, Son YM, Wang Z, Jiang L, Xiang M, Ye Z, Beckermann KE, Wu Y, Jenkins JW, Siska PJ, Vincent BG, Prakash YS, Peikert T, Edelson BT, Taneja R, Kaplan MH, Rathmell JC, Dong H, Hitosugi T, Sun J. Li C, et al. Among authors: siska pj. Immunity. 2019 Sep 17;51(3):491-507.e7. doi: 10.1016/j.immuni.2019.08.013. Immunity. 2019. PMID: 31533057 Free PMC article.
Immunometabolism in cancer at a glance.
Singer K, Cheng WC, Kreutz M, Ho PC, Siska PJ. Singer K, et al. Among authors: siska pj. Dis Model Mech. 2018 Aug 2;11(8):dmm034272. doi: 10.1242/dmm.034272. Dis Model Mech. 2018. PMID: 30076128 Free PMC article. Review.
T cell metabolic fitness in antitumor immunity.
Siska PJ, Rathmell JC. Siska PJ, et al. Trends Immunol. 2015 Apr;36(4):257-64. doi: 10.1016/j.it.2015.02.007. Epub 2015 Mar 12. Trends Immunol. 2015. PMID: 25773310 Free PMC article. Review.
Nutrients and the microenvironment to feed a T cell army.
Johnson MO, Siska PJ, Contreras DC, Rathmell JC. Johnson MO, et al. Among authors: siska pj. Semin Immunol. 2016 Oct;28(5):505-513. doi: 10.1016/j.smim.2016.09.003. Epub 2016 Oct 3. Semin Immunol. 2016. PMID: 27712958 Free PMC article. Review.
Metabolic Signaling Drives IFN-γ.
Siska PJ, Rathmell JC. Siska PJ, et al. Cell Metab. 2016 Nov 8;24(5):651-652. doi: 10.1016/j.cmet.2016.10.018. Cell Metab. 2016. PMID: 27829134 Free PMC article.
37 results