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A rapid MS/MS method to assess the deuterium kinetic isotope effect and associated improvement in the metabolic stability of deuterated biological and pharmacological molecules as applied to an imaging agent.
Murphy RB, Wyatt NA, Fraser BH, Yepuri NR, Holden PJ, Wotherspoon ATL, Darwish TA. Murphy RB, et al. Among authors: holden pj. Anal Chim Acta. 2019 Aug 8;1064:65-70. doi: 10.1016/j.aca.2019.02.025. Epub 2019 Feb 22. Anal Chim Acta. 2019. PMID: 30982519
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