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A highly invasive subpopulation of MDA-MB-231 breast cancer cells shows accelerated growth, differential chemoresistance, features of apocrine tumors and reduced tumorigenicity in vivo.
Amaro A, Angelini G, Mirisola V, Esposito AI, Reverberi D, Matis S, Maffei M, Giaretti W, Viale M, Gangemi R, Emionite L, Astigiano S, Cilli M, Bachmeier BE, Killian PH, Albini A, Pfeffer U. Amaro A, et al. Among authors: killian ph. Oncotarget. 2016 Oct 18;7(42):68803-68820. doi: 10.18632/oncotarget.11931. Oncotarget. 2016. PMID: 27626697 Free PMC article.
miR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2.
Kronski E, Fiori ME, Barbieri O, Astigiano S, Mirisola V, Killian PH, Bruno A, Pagani A, Rovera F, Pfeffer U, Sommerhoff CP, Noonan DM, Nerlich AG, Fontana L, Bachmeier BE. Kronski E, et al. Among authors: killian ph. Mol Oncol. 2014 May;8(3):581-95. doi: 10.1016/j.molonc.2014.01.005. Epub 2014 Jan 16. Mol Oncol. 2014. PMID: 24484937 Free PMC article.