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GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
Quarta C, Stemmer K, Novikoff A, Yang B, Klingelhuber F, Harger A, Bakhti M, Bastidas-Ponce A, Baugé E, Campbell JE, Capozzi M, Clemmensen C, Collden G, Cota P, Douros J, Drucker DJ, DuBois B, Feuchtinger A, Garcia-Caceres C, Grandl G, Hennuyer N, Herzig S, Hofmann SM, Knerr PJ, Kulaj K, Lalloyer F, Lickert H, Liskiewicz A, Liskiewicz D, Maity G, Perez-Tilve D, Prakash S, Sanchez-Garrido MA, Zhang Q, Staels B, Krahmer N, DiMarchi RD, Tschöp MH, Finan B, Müller TD. Quarta C, et al. Among authors: cota p. Nat Metab. 2022 Aug;4(8):1071-1083. doi: 10.1038/s42255-022-00617-6. Epub 2022 Aug 22. Nat Metab. 2022. PMID: 35995995 Free PMC article.
Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis.
Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun Ü, Lickert H. Bakhti M, et al. Among authors: cota p. Nat Commun. 2022 Aug 4;13(1):4540. doi: 10.1038/s41467-022-31862-8. Nat Commun. 2022. PMID: 35927244 Free PMC article.
β-Cell Maturation and Identity in Health and Disease.
Salinno C, Cota P, Bastidas-Ponce A, Tarquis-Medina M, Lickert H, Bakhti M. Salinno C, et al. Among authors: cota p. Int J Mol Sci. 2019 Oct 30;20(21):5417. doi: 10.3390/ijms20215417. Int J Mol Sci. 2019. PMID: 31671683 Free PMC article. Review.
Insulin regulates human pancreatic endocrine cell differentiation in vitro.
Cota P, Caliskan ÖS, Bastidas-Ponce A, Jing C, Jaki J, Saber L, Czarnecki O, Taskin D, Blöchinger AK, Kurth T, Sterr M, Burtscher I, Krahmer N, Lickert H, Bakhti M. Cota P, et al. Mol Metab. 2024 Jan;79:101853. doi: 10.1016/j.molmet.2023.101853. Epub 2023 Dec 14. Mol Metab. 2024. PMID: 38103636 Free PMC article.
CD81 marks immature and dedifferentiated pancreatic β-cells.
Salinno C, Büttner M, Cota P, Tritschler S, Tarquis-Medina M, Bastidas-Ponce A, Scheibner K, Burtscher I, Böttcher A, Theis FJ, Bakhti M, Lickert H. Salinno C, et al. Among authors: cota p. Mol Metab. 2021 Jul;49:101188. doi: 10.1016/j.molmet.2021.101188. Epub 2021 Feb 11. Mol Metab. 2021. PMID: 33582383 Free PMC article.
NEUROD2 function is dispensable for human pancreatic β cell specification.
Cota P, Saber L, Taskin D, Jing C, Bastidas-Ponce A, Vanheusden M, Shahryari A, Sterr M, Burtscher I, Bakhti M, Lickert H. Cota P, et al. Front Endocrinol (Lausanne). 2023 Oct 25;14:1286590. doi: 10.3389/fendo.2023.1286590. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37955006 Free PMC article.
Altered histone acetylation is associated with age-dependent memory impairment in mice.
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A. Peleg S, et al. Among authors: cota p. Science. 2010 May 7;328(5979):753-6. doi: 10.1126/science.1186088. Science. 2010. PMID: 20448184
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice.
Akindehin S, Liskiewicz A, Liskiewicz D, Bernecker M, Garcia-Caceres C, Drucker DJ, Finan B, Grandl G, Gutgesell R, Hofmann SM, Khalil A, Liu X, Cota P, Bakhti M, Czarnecki O, Bastidas-Ponce A, Lickert H, Kang L, Maity G, Novikoff A, Parlee S, Pathak E, Schriever SC, Sterr M, Ussar S, Zhang Q, DiMarchi R, Tschöp MH, Pfluger PT, Douros JD, Müller TD. Akindehin S, et al. Among authors: cota p. Mol Metab. 2024 Mar 14;83:101915. doi: 10.1016/j.molmet.2024.101915. Online ahead of print. Mol Metab. 2024. PMID: 38492844 Free PMC article.