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Showing results for panel mirna
Search for Pavel Mrna instead (1 results)
MicroRNA-Based Diagnosis and Therapy.
Ho PTB, Clark IM, Le LTT. Ho PTB, et al. Int J Mol Sci. 2022 Jun 28;23(13):7167. doi: 10.3390/ijms23137167. Int J Mol Sci. 2022. PMID: 35806173 Free PMC article. Review.
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene expression. ...The aim of the current review is to: (i) discuss how miRNAs traffic intracellularly and extracellularly; (ii) emphasize the role of circulating miRNAs as att
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene expression. ...The aim of the current review i
Systematic Review of miRNA as Biomarkers in Alzheimer's Disease.
Swarbrick S, Wragg N, Ghosh S, Stolzing A. Swarbrick S, et al. Mol Neurobiol. 2019 Sep;56(9):6156-6167. doi: 10.1007/s12035-019-1500-y. Epub 2019 Feb 8. Mol Neurobiol. 2019. PMID: 30734227 Free PMC article.
These deregulated miRNAs were cross-referenced against the miRNAs deregulated in the brain at Braak Stage III. This resulted in a panel of 10 miRNAs (hsa-mir-107, hsa-mir-26b, hsa-mir-30e, hsa-mir-34a, hsa-mir-485, hsa-mir200c, hsa-mir-210, hsa-mir-146 …
These deregulated miRNAs were cross-referenced against the miRNAs deregulated in the brain at Braak Stage III. This resulted i …
A novel circulating miRNA panel for non-invasive ovarian cancer diagnosis and prognosis.
Gahlawat AW, Witte T, Haarhuis L, Schott S. Gahlawat AW, et al. Br J Cancer. 2022 Nov;127(8):1550-1556. doi: 10.1038/s41416-022-01925-0. Epub 2022 Aug 5. Br J Cancer. 2022. PMID: 35931806 Free PMC article.
METHODS: In this study, we investigated total circulating cell-free microRNA (cf-miRNA) levels as well as a panel of cf-miRNAs in the plasma of OC patients (n = 100), patients with benign lesions (n = 45) and healthy controls (n = 99). ...Importantly, in comb …
METHODS: In this study, we investigated total circulating cell-free microRNA (cf-miRNA) levels as well as a panel of cf-miR
Selecting optimum miRNA panel for miRNA signature-based companion diagnostic model to predict the response of R-CHOP treatment in diffuse large B-cell lymphoma.
Nakamura N, Hamada R, Kaneko H, Ohta S. Nakamura N, et al. J Biosci Bioeng. 2023 Apr;135(4):341-347. doi: 10.1016/j.jbiosc.2023.01.005. Epub 2023 Jan 31. J Biosci Bioeng. 2023. PMID: 36732209
To select the optimum miRNA combination as a panel, we examined three feature selection methods (p-value-based ranking, stepwise method, and Boruta), together with 11 types of classifiers systematically. ...The AUC value first increased with an increasing number of …
To select the optimum miRNA combination as a panel, we examined three feature selection methods (p-value-based ranking, stepwi …
A Liquid Biopsy Signature for the Detection of Patients With Early-Onset Colorectal Cancer.
Nakamura K, Hernández G, Sharma GG, Wada Y, Banwait JK, González N, Perea J, Balaguer F, Takamaru H, Saito Y, Toiyama Y, Kodera Y, Boland CR, Bujanda L, Quintero E, Goel A. Nakamura K, et al. Gastroenterology. 2022 Nov;163(5):1242-1251.e2. doi: 10.1053/j.gastro.2022.06.089. Epub 2022 Jul 16. Gastroenterology. 2022. PMID: 35850198 Free PMC article.
The miRNA panel performance was then confirmed in an independent validation cohort (area under the curve, 0.88; 95% confidence interval, 0.82-0.93). Moreover, the miRNA panel robustly identified patients with early-stage EOCRC (P < .001). ...
The miRNA panel performance was then confirmed in an independent validation cohort (area under the curve, 0.88; 95% confidence …
Bladder cancer diagnosis with a four-miRNA panel in serum.
Li X, Chen W, Li R, Chen X, Huang G, Lu C, Wen Z, Peng X, Liu K, Zhang C, Li H, Hu Y, Zhao Z, Tao L, Lai Y. Li X, et al. Future Oncol. 2022 Sep;18(29):3311-3322. doi: 10.2217/fon-2022-0448. Epub 2022 Sep 1. Future Oncol. 2022. PMID: 36047424 Free article. Clinical Trial.
A total of 15 candidate miRNAs were selected, and miRNAs with diagnostic ability were screened out with quantitative reverse transcription PCR. ...Conclusion: This four-miRNA panel could represent a stable biomarker for bladder cancer diagnosis. ...
A total of 15 candidate miRNAs were selected, and miRNAs with diagnostic ability were screened out with quantitative reverse t …
Use of a Four-miRNA Panel as a Biomarker for the Diagnosis of Stomach Adenocarcinoma.
Chen X, Li X, Peng X, Zhang C, Liu K, Huang G, Lai Y. Chen X, et al. Dis Markers. 2020 Nov 7;2020:8880937. doi: 10.1155/2020/8880937. eCollection 2020. Dis Markers. 2020. PMID: 33224315 Free PMC article.
BACKGROUND: MicroRNAs (miRNAs) have been applied to cancer diagnosis taking into account their role in tumorigenesis. ...Only miR-125b-5p expression showed a significant difference between STAD patients and NCs in the survival analysis. The neurotrophin signaling pa …
BACKGROUND: MicroRNAs (miRNAs) have been applied to cancer diagnosis taking into account their role in tumorigenesis. ...Only …
Preliminary study using a small plasma extracellular vesicle miRNA panel as a potential biomarker for early diagnosis and prognosis in laryngeal cancer.
Zhang H, Chen Z, Huang Q, Guo Y, Wang M, Wu C. Zhang H, et al. Cell Oncol (Dordr). 2023 Aug;46(4):1015-1030. doi: 10.1007/s13402-023-00792-y. Epub 2023 Mar 25. Cell Oncol (Dordr). 2023. PMID: 36964893
PURPOSE: Plasma extracellular vesicle (EV) miRNAs are important biomarkers for body fluid biopsy. The purpose of this study was to screen and construct a plasma small EV (sEV) miRNA panel as a biomarker for diagnosis and prognosis in laryngeal squamous cell c …
PURPOSE: Plasma extracellular vesicle (EV) miRNAs are important biomarkers for body fluid biopsy. The purpose of this study was to sc …
Exosomes and their miRNA/protein profile in keratoconus-derived corneal stromal cells.
Hadvina R, Lotfy Khaled M, Akoto T, Zhi W, Karamichos D, Liu Y. Hadvina R, et al. Exp Eye Res. 2023 Nov;236:109642. doi: 10.1016/j.exer.2023.109642. Epub 2023 Sep 14. Exp Eye Res. 2023. PMID: 37714423
Different exosomal markers were identified and quantified using a transmission electron microscope (TEM) (CD81) and Western blot (CD9 and CD63). Exosomal miRNA profiles were determined by qRT-PCR using Exiqon Human panel I miRNA assays of 368 pre-selected …
Different exosomal markers were identified and quantified using a transmission electron microscope (TEM) (CD81) and Western blot (CD9 and CD …
Exosomal miRNA Biomarker Panel for Pancreatic Ductal Adenocarcinoma Detection in Patient Plasma: A Pilot Study.
Makler A, Asghar W. Makler A, et al. Int J Mol Sci. 2023 Mar 7;24(6):5081. doi: 10.3390/ijms24065081. Int J Mol Sci. 2023. PMID: 36982154 Free PMC article.

PDAC-associated miRNAs packaged within these exosomes could be used as diagnostic markers. We analyzed a series of 18 candidate miRNAs via RT-qPCR to identify the differentially expressed miRNAs (p < 0.05, t-test) between plasma exosomes harvested from PDA

PDAC-associated miRNAs packaged within these exosomes could be used as diagnostic markers. We analyzed a series of 18 candidate mi
2,775 results