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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 4
2004 1
2005 3
2006 3
2007 2
2008 2
2010 1
2013 1
2014 4
2015 3
2016 8
2017 9
2018 7
2019 7
2020 7
2021 4
2022 7
2023 9
2024 0

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75 results

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Page 1
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug.
Rais R, Lemberg KM, Tenora L, Arwood ML, Pal A, Alt J, Wu Y, Lam J, Aguilar JMH, Zhao L, Peters DE, Tallon C, Pandey R, Thomas AG, Dash RP, Seiwert T, Majer P, Leone RD, Powell JD, Slusher BS. Rais R, et al. Among authors: majer p. Sci Adv. 2022 Nov 18;8(46):eabq5925. doi: 10.1126/sciadv.abq5925. Epub 2022 Nov 16. Sci Adv. 2022. PMID: 36383674 Free PMC article.
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis.
Peters DE, Norris LD, Tenora L, Šnajdr I, Ponti AK, Zhu X, Sakamoto S, Veeravalli V, Pradhan M, Alt J, Thomas AG, Majer P, Rais R, McDonald C, Slusher BS. Peters DE, et al. Among authors: majer p. Sci Transl Med. 2023 Aug 9;15(708):eabn7491. doi: 10.1126/scitranslmed.abn7491. Epub 2023 Aug 9. Sci Transl Med. 2023. PMID: 37556558 Free PMC article.
Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata.
Tsai J, Gori S, Alt J, Tiwari S, Iyer J, Talwar R, Hinsu D, Ahirwar K, Mohanty S, Khunt C, Sutariya B, Jani K, Venkatasubbaiah V, Patel A, Meghapara J, Joshi K, Sahu R, Rana V, Nigade P, Talluri RS, Murty KVSN, Joshi K, Ramanathan V, Li A, Islam N, Snajdr I, Majer P, Rais R, Slusher BS, Garza LA. Tsai J, et al. Among authors: majer p. PNAS Nexus. 2022 Dec 16;2(1):pgac297. doi: 10.1093/pnasnexus/pgac297. eCollection 2023 Jan. PNAS Nexus. 2022. PMID: 36712931 Free PMC article.
Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor.
Lemberg KM, Ali ES, Krecmerova M, Aguilar JMH, Alt J, Peters DE, Zhao L, Wu Y, Nuha N, Asara JM, Staedtke V, Pratilas CA, Majer P, Rais R, Ben-Sahra I, Slusher BS. Lemberg KM, et al. Among authors: majer p. Mol Cancer Ther. 2023 Dec 1;22(12):1390-1403. doi: 10.1158/1535-7163.MCT-23-0258. Mol Cancer Ther. 2023. PMID: 37616542 Free PMC article.
The combination of immunotherapy and a glutamine metabolism inhibitor represents an effective therapeutic strategy for advanced and metastatic murine pancreatic adenocarcinoma.
Frejlachova A, Lencova R, Venhauerova A, Skalickova M, Uher O, Caisova V, Majer P, Tenora L, Hansen P, Chmelar J, Kopecky J, Zhuang Z, Pacak K, Zenka J. Frejlachova A, et al. Among authors: majer p. Int Immunopharmacol. 2023 May;118:110150. doi: 10.1016/j.intimp.2023.110150. Epub 2023 Apr 6. Int Immunopharmacol. 2023. PMID: 37030115
Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery.
Novotná K, Tenora L, Prchalová E, Paule J, Alt J, Veeravalli V, Lam J, Wu Y, Šnajdr I, Gori S, Mettu VS, Tsukamoto T, Majer P, Slusher BS, Rais R. Novotná K, et al. Among authors: majer p. J Med Chem. 2023 Nov 23;66(22):15493-15510. doi: 10.1021/acs.jmedchem.3c01681. Epub 2023 Nov 10. J Med Chem. 2023. PMID: 37949450 Free PMC article.
75 results