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Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy.
Mol Cancer Ther. 2023 Jul 5;22(7):807-817. doi: 10.1158/1535-7163.MCT-22-0721.
Mol Cancer Ther. 2023.
PMID: 36939275
Potent but transient immunosuppression of T-cells is a general feature of CD71+ erythroid cells.
Grzywa TM, Sosnowska A, Rydzynska Z, Lazniewski M, Plewczynski D, Klicka K, Malecka-Gieldowska M, Rodziewicz-Lurzynska A, Ciepiela O, Justyniarska M, Pomper P, Grzybowski MM, Blaszczyk R, Wegrzynowicz M, Tomaszewska A, Basak G, Golab J, Nowis D.
Grzywa TM, et al. Among authors: pomper p.
Commun Biol. 2021 Dec 10;4(1):1384. doi: 10.1038/s42003-021-02914-4.
Commun Biol. 2021.
PMID: 34893694
Free PMC article.
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OATD-02 Validates the Benefits of Pharmacological Inhibition of Arginase 1 and 2 in Cancer.
Grzybowski MM, Stańczak PS, Pomper P, Błaszczyk R, Borek B, Gzik A, Nowicka J, Jędrzejczak K, Brzezińska J, Rejczak T, Güner-Chalimoniuk NC, Kikulska A, Mlącki M, Pęczkowicz-Szyszka J, Olczak J, Gołębiowski A, Dzwonek K, Dobrzański P, Zasłona Z.
Grzybowski MM, et al. Among authors: pomper p.
Cancers (Basel). 2022 Aug 17;14(16):3967. doi: 10.3390/cancers14163967.
Cancers (Basel). 2022.
PMID: 36010962
Free PMC article.
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