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A dual-acting 5-HT6 receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties.
Eur J Med Chem. 2020 Dec 15;208:112765. doi: 10.1016/j.ejmech.2020.112765. Epub 2020 Aug 22.
Eur J Med Chem. 2020.
PMID: 32949963
Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT1A receptor partial agonists.
Partyka A, Zagórska A, Kotańska M, Walczak M, Jastrzębska-Więsek M, Knutelska J, Bednarski M, Głuch-Lutwin M, Mordyl B, Janiszewska P, Wesołowska A.
Partyka A, et al. Among authors: janiszewska p.
PLoS One. 2020 Aug 7;15(8):e0237196. doi: 10.1371/journal.pone.0237196. eCollection 2020.
PLoS One. 2020.
PMID: 32764777
Free PMC article.
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Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system.
Żelaszczyk D, Jakubczyk M, Pytka K, Rapacz A, Walczak M, Janiszewska P, Pańczyk K, Żmudzki P, Słoczyńska K, Marona H, Waszkielewicz AM.
Żelaszczyk D, et al. Among authors: janiszewska p.
Bioorg Med Chem Lett. 2019 Nov 1;29(21):126679. doi: 10.1016/j.bmcl.2019.126679. Epub 2019 Sep 9.
Bioorg Med Chem Lett. 2019.
PMID: 31537425
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HBK-15 protects mice from stress-induced behavioral disturbances and changes in corticosterone, BDNF, and NGF levels.
Pytka K, Głuch-Lutwin M, Kotańska M, Żmudzka E, Jakubczyk M, Waszkielewicz A, Janiszewska P, Walczak M.
Pytka K, et al. Among authors: janiszewska p.
Behav Brain Res. 2017 Aug 30;333:54-66. doi: 10.1016/j.bbr.2017.06.032. Epub 2017 Jun 23.
Behav Brain Res. 2017.
PMID: 28648684
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