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Copper(II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1,10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper(II) Compound.
Bontempo NJS, Paixão DA, Lima PMAP, Barros DCT, Borges DS, Orsolin PC, Martins IC, Machado PHA, Lino RC, Souza TR, Ramos LMS, Teixeira SC, Siqueira RP, Goulart Filho LR, Guerra W, Oliveira Júnior RJ, Araújo TG. Bontempo NJS, et al. Molecules. 2022 Oct 20;27(20):7097. doi: 10.3390/molecules27207097. Molecules. 2022. PMID: 36296690 Free PMC article.
A selective CuII complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells.
Machado PHA, Paixão DA, Lino RC, de Souza TR, de Souza Bontempo NJ, Sousa LM, Van Petten de Vasconcelos Azevedo F, Orsolin PC, Lima PMAP, Martins IC, da Costa Guerra JF, Teixeira SC, Araújo TG, Goulart LR, Morelli S, Guerra W, de Oliveira Júnior RJ. Machado PHA, et al. Sci Rep. 2021 Dec 27;11(1):24450. doi: 10.1038/s41598-021-03909-1. Sci Rep. 2021. PMID: 34961767 Free PMC article.
Action of copper(II) complex with β-diketone and 1,10-phenanthroline (CBP-01) on sarcoma cells and biological effects under cell death.
Polloni L, Seni Silva AC, Teixeira SC, Azevedo FVPV, Zóia MAP, da Silva MS, Lima PMAP, Correia LIV, do Couto Almeida J, da Silva CV, Rodrigues Ávila VM, Goulart LRF, Morelli S, Guerra W, Oliveira Júnior RJ. Polloni L, et al. Biomed Pharmacother. 2019 Apr;112:108586. doi: 10.1016/j.biopha.2019.01.047. Epub 2019 Feb 18. Biomed Pharmacother. 2019. PMID: 30784909 Free article.