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2017 2
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Page 1
Acute and chronic neurological consequences of early-life Zika virus infection in mice.
Nem de Oliveira Souza I, Frost PS, França JV, Nascimento-Viana JB, Neris RLS, Freitas L, Pinheiro DJLL, Nogueira CO, Neves G, Chimelli L, De Felice FG, Cavalheiro ÉA, Ferreira ST, Assunção-Miranda I, Figueiredo CP, Da Poian AT, Clarke JR. Nem de Oliveira Souza I, et al. Among authors: frost ps. Sci Transl Med. 2018 Jun 6;10(444):eaar2749. doi: 10.1126/scitranslmed.aar2749. Sci Transl Med. 2018. PMID: 29875203
Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice.
Figueiredo CP, Barros-Aragão FGQ, Neris RLS, Frost PS, Soares C, Souza INO, Zeidler JD, Zamberlan DC, de Sousa VL, Souza AS, Guimarães ALA, Bellio M, Marcondes de Souza J, Alves-Leon SV, Neves GA, Paula-Neto HA, Castro NG, De Felice FG, Assunção-Miranda I, Clarke JR, Da Poian AT, Ferreira ST. Figueiredo CP, et al. Among authors: frost ps. Nat Commun. 2019 Sep 5;10(1):3890. doi: 10.1038/s41467-019-11866-7. Nat Commun. 2019. PMID: 31488835 Free PMC article.
Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice.
Frost PS, Barros-Aragão F, da Silva RT, Venancio A, Matias I, Lyra E Silva NM, Kincheski GC, Pimentel-Coelho PM, De Felice FG, Gomes FCA, Ferreira ST, Figueiredo CP, Clarke JR. Frost PS, et al. Cell Death Dis. 2019 Apr 11;10(4):323. doi: 10.1038/s41419-019-1529-x. Cell Death Dis. 2019. PMID: 30975983 Free PMC article.
Zika Virus Infects, Activates, and Crosses Brain Microvascular Endothelial Cells, without Barrier Disruption.
Papa MP, Meuren LM, Coelho SVA, Lucas CGO, Mustafá YM, Lemos Matassoli F, Silveira PP, Frost PS, Pezzuto P, Ribeiro MR, Tanuri A, Nogueira ML, Campanati L, Bozza MT, Paula Neto HA, Pimentel-Coelho PM, Figueiredo CP, de Aguiar RS, de Arruda LB. Papa MP, et al. Among authors: frost ps. Front Microbiol. 2017 Dec 22;8:2557. doi: 10.3389/fmicb.2017.02557. eCollection 2017. Front Microbiol. 2017. PMID: 29312238 Free PMC article.
Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson's disease-like symptoms in mice.
Fortuna JTS, Gralle M, Beckman D, Neves FS, Diniz LP, Frost PS, Barros-Aragão F, Santos LE, Gonçalves RA, Romão L, Zamberlan DC, Soares FAA, Braga C, Foguel D, Gomes FCA, De Felice FG, Ferreira ST, Clarke JR, Figueiredo CP. Fortuna JTS, et al. Among authors: frost ps. Behav Brain Res. 2017 Aug 30;333:150-160. doi: 10.1016/j.bbr.2017.06.047. Epub 2017 Jun 29. Behav Brain Res. 2017. PMID: 28668282