Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors.
Kwon SG, Roh DH, Yoon SY, Choi SR, Choi HS, Moon JY, Kang SY, Kim HW, Han HJ, Beitz AJ, Oh SB, Lee JH.
Kwon SG, et al.
Eur J Pain. 2016 Apr;20(4):594-606. doi: 10.1002/ejp.774. Epub 2015 Sep 11.
Eur J Pain. 2016.
PMID: 26358747
In naive rats, i.pl. injection of Sig-1R agonist PRE-084 alone did not produce MA; but it did induce MA when co-administered with either an acidic pH solution or a sub-effective dose of alphabetameATP. CONCLUSION: Peripheral Sig-1Rs contribute to the induction of ischaemia …
In naive rats, i.pl. injection of Sig-1R agonist PRE-084 alone did not produce MA; but it did induce MA when co-administered with either an …