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Page 1
Ribose-modified mizoribine analogues: synthesis and biological evaluation.
Franchetti P, Pasqualini M, Cappellacci L, Petrelli R, Vita P, Grifantini M. Franchetti P, et al. Among authors: vita p. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):2023-7. doi: 10.1080/15257770500334673. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438062
From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine.
Petrelli R, Meli M, Vita P, Torquati I, Ferro A, Vodnala M, D'Alessandro N, Tolomeo M, Del Bello F, Kusumanchi P, Franchetti P, Grifantini M, Jayaram HN, Hofer A, Cappellacci L. Petrelli R, et al. Among authors: vita p. Bioorg Med Chem Lett. 2014 Nov 15;24(22):5304-9. doi: 10.1016/j.bmcl.2014.09.046. Epub 2014 Sep 28. Bioorg Med Chem Lett. 2014. PMID: 25304896
N6-Cycloalkyl- and N6-bicycloalkyl-C5'(C2')-modified adenosine derivatives as high-affinity and selective agonists at the human A1 adenosine receptor with antinociceptive effects in mice.
Franchetti P, Cappellacci L, Vita P, Petrelli R, Lavecchia A, Kachler S, Klotz KN, Marabese I, Luongo L, Maione S, Grifantini M. Franchetti P, et al. Among authors: vita p. J Med Chem. 2009 Apr 23;52(8):2393-406. doi: 10.1021/jm801456g. J Med Chem. 2009. PMID: 19317449
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions.
Luongo L, Petrelli R, Gatta L, Giordano C, Guida F, Vita P, Franchetti P, Grifantini M, de Novellis V, Cappellacci L, Maione S. Luongo L, et al. Among authors: vita p. Molecules. 2012 Nov 22;17(12):13712-26. doi: 10.3390/molecules171213712. Molecules. 2012. PMID: 23174891 Free PMC article.
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives.
Cappellacci L, Franchetti P, Vita P, Petrelli R, Lavecchia A, Jayaram HN, Saiko P, Graser G, Szekeres T, Grifantini M. Cappellacci L, et al. Among authors: vita p. J Med Chem. 2008 Jul 24;51(14):4260-9. doi: 10.1021/jm800205c. Epub 2008 Jun 28. J Med Chem. 2008. PMID: 18588281
12 results