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Page 1
The ammonium sulfate inhibition of human angiogenin.
Chatzileontiadou DS, Tsirkone VG, Dossi K, Kassouni AG, Liggri PG, Kantsadi AL, Stravodimos GA, Balatsos NA, Skamnaki VT, Leonidas DD. Chatzileontiadou DS, et al. Among authors: liggri pg. FEBS Lett. 2016 Sep;590(17):3005-18. doi: 10.1002/1873-3468.12335. Epub 2016 Aug 12. FEBS Lett. 2016. PMID: 27483019 Free article.
Influence of pH on indole-dependent heterodimeric interactions between Anopheles gambiae odorant-binding proteins OBP1 and OBP4.
Mam B, Tsitsanou KE, Liggri PGV, Saitta F, Stamati ECV, Mahita J, Leonis G, Drakou CE, Papadopoulos M, Arnaud P, Offmann B, Fessas D, Sowdhamini R, Zographos SE. Mam B, et al. Among authors: liggri pgv. Int J Biol Macromol. 2023 Aug 1;245:125422. doi: 10.1016/j.ijbiomac.2023.125422. Epub 2023 Jun 16. Int J Biol Macromol. 2023. PMID: 37330089
Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography.
Szabó KE, Kyriakis E, Psarra AG, Karra AG, Sipos Á, Docsa T, Stravodimos GA, Katsidou E, Skamnaki VT, Liggri PGV, Zographos SE, Mándi A, Király SB, Kurtán T, Leonidas DD, Somsák L. Szabó KE, et al. Among authors: liggri pgv. J Med Chem. 2019 Jul 11;62(13):6116-6136. doi: 10.1021/acs.jmedchem.9b00356. Epub 2019 Jun 28. J Med Chem. 2019. PMID: 31251604
Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase.
Stravodimos GA, Kantsadi AL, Apostolou A, Kyriakis E, Kafaski-Kanelli VN, Solovou T, Gatzona P, Liggri PGV, Theofanous S, Gorgogietas VA, Kissa A, Psachoula C, Lemonakis A, Chatzileontiadou DSM, Psarra AG, Skamnaki VT, Haroutounian SA, Leonidas DD. Stravodimos GA, et al. Among authors: liggri pgv. Curr Drug Discov Technol. 2018;15(1):41-53. doi: 10.2174/1570163814666170619091736. Curr Drug Discov Technol. 2018. PMID: 28625148
High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors.
Fischer T, Koulas SM, Tsagkarakou AS, Kyriakis E, Stravodimos GA, Skamnaki VT, Liggri PGV, Zographos SE, Riedl R, Leonidas DD. Fischer T, et al. Among authors: liggri pgv. Molecules. 2019 Apr 3;24(7):1322. doi: 10.3390/molecules24071322. Molecules. 2019. PMID: 30987252 Free PMC article.
The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design.
Kyriakis E, Karra AG, Papaioannou O, Solovou T, Skamnaki VT, Liggri PGV, Zographos SE, Szennyes E, Bokor É, Kun S, Psarra AG, Somsák L, Leonidas DD. Kyriakis E, et al. Among authors: liggri pgv. Bioorg Med Chem. 2020 Jan 1;28(1):115196. doi: 10.1016/j.bmc.2019.115196. Epub 2019 Nov 14. Bioorg Med Chem. 2020. PMID: 31767404