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Physico-Chemical, In Vitro and Ex Vivo Characterization of Meloxicam Potassium-Cyclodextrin Nanospheres.
Varga P, Ambrus R, Szabó-Révész P, Kókai D, Burián K, Bella Z, Fenyvesi F, Bartos C. Varga P, et al. Pharmaceutics. 2021 Nov 6;13(11):1883. doi: 10.3390/pharmaceutics13111883. Pharmaceutics. 2021. PMID: 34834298 Free PMC article.
As a result of spray drying, mucoadhesive nanospheres (average particle size <1 m) were prepared which contained amorphous MEL-P. Cyclodextrin-MEL-P complexes were formed and the applied excipients increased the in vitro and ex vivo permeability of MEL-P. …
As a result of spray drying, mucoadhesive nanospheres (average particle size <1 m) were prepared which contained amorphous MEL-P. …
Drug reservoir function of human amniotic membrane.
Resch MD, Resch BE, Csizmazia E, Imre L, Németh J, Szabó-Révész P, Csányi E. Resch MD, et al. J Ocul Pharmacol Ther. 2011 Aug;27(4):323-6. doi: 10.1089/jop.2011.0007. Epub 2011 Jun 24. J Ocul Pharmacol Ther. 2011. PMID: 21702686
Released ofloxacin in Group 1 was significantly lower than in Group 2 after 90 min (19.410.4 mug/cm(2), 51.620.7 mug/cm(2), respectively, P=0.044). In Group 3, cumulative drug release was higher than in Group at all timepoints. ...
Released ofloxacin in Group 1 was significantly lower than in Group 2 after 90 min (19.410.4 mug/cm(2), 51.620.7 mug/cm(2), respectively, …
Rheological effects of hypertonic saline and sodium bicarbonate solutions on cystic fibrosis sputum in vitro.
Budai-Szűcs M, Berkó S, Kovács A, Jaikumpun P, Ambrus R, Halász A, Szabó-Révész P, Csányi E, Zsembery Á. Budai-Szűcs M, et al. BMC Pulm Med. 2021 Jul 12;21(1):225. doi: 10.1186/s12890-021-01599-z. BMC Pulm Med. 2021. PMID: 34253193 Free PMC article.

At the higher additive ratio (10:4), all of the added solutions were found to significantly reduce the gel strength of the sputum, but the most pronounced changes were observed with NaHCO(3) (p < 0.001). Samples with high elasticity exhibited the greatest changes while,

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At the higher additive ratio (10:4), all of the added solutions were found to significantly reduce the gel strength of the sputum, but the m …
Sucrose esters increase drug penetration, but do not inhibit p-glycoprotein in caco-2 intestinal epithelial cells.
Kiss L, Hellinger É, Pilbat AM, Kittel Á, Török Z, Füredi A, Szakács G, Veszelka S, Sipos P, Ózsvári B, Puskás LG, Vastag M, Szabó-Révész P, Deli MA. Kiss L, et al. J Pharm Sci. 2014 Oct;103(10):3107-19. doi: 10.1002/jps.24085. Epub 2014 Jul 16. J Pharm Sci. 2014. PMID: 25042090
Sucrose esters fluidized the plasma membrane and enhanced the accumulation of efflux transporter ligands rhodamine 123 and calcein AM in epithelial cells, but did not inhibit the P-glycoprotein (P-gp)-mediated calcein AM accumulation in MES-SA/Dx5 cell line. These d …
Sucrose esters fluidized the plasma membrane and enhanced the accumulation of efflux transporter ligands rhodamine 123 and calcein AM in epi …
Preparation and investigation of mefenamic acid - polyethylene glycol - sucrose ester solid dispersions.
Fülöp I, Gyéresi Á, Kiss L, Deli MA, Croitoru MD, Szabó-Révész P, Aigner Z. Fülöp I, et al. Acta Pharm. 2015 Dec;65(4):453-62. doi: 10.1515/acph-2015-0035. Acta Pharm. 2015. PMID: 26677901 Free article.
Solid dispersions of MA were prepared by the melting method using polyethylene glycol 6000 and different types (laurate, D-1216; palmitate, P-1670; stearate, S-1670) and amounts of sucrose esters as carriers. ...
Solid dispersions of MA were prepared by the melting method using polyethylene glycol 6000 and different types (laurate, D-1216; palmitate, …
Formulation optimization of sustained-release ammonio methacrylate copolymer microspheres. Effects of log p and concentration of polar cosolvents, and role of the drug/copolymer ratio.
Sipos P, Rajkó R, Pintye-Hódi K, Erős I, Szabó-Révész P. Sipos P, et al. Pharmaceutics. 2011 Nov 10;3(4):830-47. doi: 10.3390/pharmaceutics3040830. Pharmaceutics. 2011. PMID: 24309310 Free PMC article.
The objectives of this work were the formulation optimization of the preparation process parameters and to evaluate spray-dried sustained-release microspheres using ammonio methacrylate copolymer (AMC) as a polymer matrix. The effects of log P and the concentrations of the …
The objectives of this work were the formulation optimization of the preparation process parameters and to evaluate spray-dried sustained-re …